SymbolAARD
NameAARDVARK THERAPEUTICS, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address4370 LA JOLLA VILLAGE DRIVE,SUITE 1050, SAN DIEGO, California, 92122, United States
Telephone(858) 225-7696
Fax
Email
Websitehttps://www.aardvarktherapeutics.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001774857
Description

Aardvark Therapeutics is a clinical-stage biopharmaceutical company focused on developing novel, small-molecule therapeutics to activate innate homeostatic pathways for the treatment of metabolic diseases. We have focused our efforts on developing selective compounds, targeting Bitter Taste Receptors (TAS2Rs) for hunger-associated conditions. Our wholly-owned lead product candidate, ARD-101 (denatonium acetate monohydrate), is an oral gut-restricted small-molecule agonist of certain TAS2Rs expressed in the gut lumen for which we have initiated a Phase 3 clinical trial for hyperphagia associated with Prader-Willi Syndrome (PWS). We also intend to evaluate ARD-101 in a Phase 2 clinical trial for hyperphagia associated with acquired hypothalamic obesity resultant from treatment of craniopharyngioma, including surgery or radiation (HO).

Additional info from NASDAQ:
Aardvark Therapeutics is a clinical-stage biopharmaceutical company focused on developing novel, small-molecule therapeutics to activate innate homeostatic pathways for the treatment of metabolic diseases. We have focused our efforts on developing selective compounds, targeting Bitter Taste Receptors (TAS2Rs) for hunger-associated conditions. Our wholly-owned lead product candidate, ARD-101 (denatonium acetate monohydrate), is an oral gut-restricted small-molecule agonist of certain TAS2Rs expressed in the gut lumen for which we have initiated a Phase 3 clinical trial for hyperphagia associated with Prader-Willi Syndrome (PWS). We also intend to evaluate ARD-101 in a Phase 2 clinical trial for hyperphagia associated with acquired hypothalamic obesity resultant from treatment of craniopharyngioma, including surgery or radiation (HO).

2026-06-25 13:00

Aardvark Therapeutics (AARD) Faces Investor Scrutiny Amid 56% Drop On Clinical Pause For Lead Drug Candidate- HBSS

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2026-06-19 13:00

Aardvark Therapeutics (AARD) Faces Investor Scrutiny Amid 56% Drop On Clinical Pause For Lead Drug Candidate- HBSS

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2026-06-12 20:05

(99% Neutral) AARDVARK THERAPEUTICS, INC. (AARD) Announces Executive Changes

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2026-06-11 14:00

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Aardvark Therapeutics, Inc. - AARD

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2026-05-28 14:00

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Aardvark Therapeutics, Inc. - AARD

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2026-05-28 13:00

Aardvark Therapeutics (AARD) Faces Investor Scrutiny Amid 56% Drop On Clinical Pause For Lead Drug Candidate- HBSS

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2026-05-21 22:40

INVESTOR ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Aardvark Therapeutics, Inc. - AARD

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2026-05-21 13:00

Aardvark Therapeutics (AARD) Faces Investor Scrutiny Amid 56% Drop On Clinical Pause For Lead Drug Candidate- HBSS

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2026-05-19 16:30

Aardvark Therapeutics (AARD) Faces Investor Scrutiny Amid 56% Drop On Clinical Pause For Lead Drug Candidate- Hagens Berman

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2026-05-14 20:15

(19% Negative) AARDVARK THERAPEUTICS, INC. (AARD) Announces Delay in pathways Trials for Prader Due to Patient Enrollment Issues, Manufacturing Considerations, Safety Review, Efficacy Assessment

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT06828861 ARD-101 for Treatment of PWS: The Hunger Elimination or Reduction Objective Tri… Phase3 Hyperphagia Terminated 2024-12-20 2026-05-07 ClinicalTrials.gov
NCT06126653 A Study to Evaluate ARD-501 in Patients With Autism Spectrum Disorder Phase2 Autism Spectrum Disorder Completed 2024-08-01 2025-01-13 ClinicalTrials.gov
NCT07197034 The Hunger Elimination or Reduction Objective (HERO ) Open -Label Extension (OL… Phase3 Hyperphagia Terminated 2024-07-23 2026-04-15 ClinicalTrials.gov
NCT05153434 A Study of Oral ARD-101 in Patients With Prader-Willi Syndrome Phase2 Prader-Willi Syndrome Completed 2022-05-27 2024-09-24 ClinicalTrials.gov
NCT05215847 Study to Evaluate ARD-101 in Adults Receiving Bariatric Surgery Phase2 Bariatric Surgery Completed 2022-03-01 2023-02-03 ClinicalTrials.gov
NCT05121441 Study to Evaluate ARD-101 in Adults With Obesity Phase2 Obesity Completed 2021-11-15 2022-11-09 ClinicalTrials.gov
NCT01129765 Home Usability of a Nasal Lavage System in Children Nasal Congestion Completed 2009-07-01 2009-08-01 ClinicalTrials.gov
Total clinical trials: 7
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
ARD-101 Other Phase PHASE3 Hyperphagia TERMINATED NCT06828861
Placebo Other Phase PHASE3 Hyperphagia TERMINATED NCT06828861
ARD-101 Other Phase PHASE3 Hyperphagia TERMINATED NCT07197034
Use of an automatic nasal irrigator/aspirator Other Preclinical Nasal Congestion COMPLETED NCT01129765
Placebo Other Phase PHASE2 Obesity COMPLETED NCT05121441
ARD-101 Other Phase PHASE2 Obesity COMPLETED NCT05121441
ARD-101 Other Phase PHASE2 Bariatric Surgery COMPLETED NCT05215847
Placebo Other Phase PHASE2 Autism Spectrum Disorder COMPLETED NCT06126653
High Dose ARD-501 Other Phase PHASE2 Autism Spectrum Disorder COMPLETED NCT06126653
Low Dose ARD-501 Other Phase PHASE2 Autism Spectrum Disorder COMPLETED NCT06126653
ARD-101 Other Phase PHASE2 Prader-Willi Syndrome COMPLETED NCT05153434
ARD-101 Other Phase PHASE3 Hyperphagia SUSPENDED NCT07197034
ARD-101 Other Phase PHASE3 Hyperphagia SUSPENDED NCT06828861
Placebo Other Phase PHASE3 Hyperphagia SUSPENDED NCT06828861
High Dose ARD-501 DRUG Phase PHASE2 Autism Spectrum Disorder COMPLETED NCT06126653
Low Dose ARD-501 DRUG Phase PHASE2 Autism Spectrum Disorder COMPLETED NCT06126653
Placebo DRUG Phase PHASE3 Hyperphagia SUSPENDED NCT06828861
ARD-101 DRUG Phase PHASE3 Hyperphagia SUSPENDED NCT07197034
Total products: 18