SymbolACHV
NameACHIEVE LIFE SCIENCES, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: In Vitro & In Vivo Diagnostic Substances
Address22722 29TH DRIVE SOUTHEAST,SUITE 100, BOTHELL, British Columbia, WA 98021, Canada
Telephone+1 604 210-2217
Fax
Email
Websitehttps://www.achievelifesciences.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK
Description

Achieve Life Sciences Inc is a specialty pharmaceutical company committed to advancing cytisinicline as a widely available treatment option to help people battling nicotine addiction. It is an established smoking cessation treatment that has been approved and marketed in Central and Eastern Europe. Achieves focus is to address the global smoking health epidemic through the development and commercialization of cytisinicline.

Additional info from NASDAQ:
Achieve Life Sciences Inc is a specialty pharmaceutical company committed to advancing cytisinicline as a widely available treatment option to help people battling nicotine addiction. It is an established smoking cessation treatment that has been approved and marketed in Central and Eastern Europe. Achieves focus is to address the global smoking health epidemic through the development and commercialization of cytisinicline.

2026-04-21 22:20

Goldberg Andrew D. 🟢 acquired 17.1M shares (3 derivative) of ACHIEVE LIFE SCIENCES, INC. (ACHV) at $4.25 ($15.3M) Transaction Date: Apr 18, 2026 | Filing ID: 167418

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2026-04-21 19:17

New Form 3 - ACHIEVE LIFE SCIENCES, INC. <b>Filed:</b> 2026-04-21 <b>AccNo:</b> 0001193125-26-167404 <b>Size:</b> 18 KB

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2026-04-16 20:47

(85% Positive) ACHIEVE LIFE SCIENCES, INC. (ACHV) Provides Update on treatment for nicotine dependence

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2026-04-16 17:12

New Form S-8 - ACHIEVE LIFE SCIENCES, INC. <b>Filed:</b> 2026-04-16 <b>AccNo:</b> 0001193125-26-159016 <b>Size:</b> 879 KB

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2026-04-16 12:57

Achieve Life Sciences Announces Appointment of Andrew D. Goldberg, MD, as Chief Executive Officer and to the Board of Directors

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2026-04-16 12:57

Achieve Life Sciences Announces Appointment of Andrew D. Goldberg, MD, as Chief Executive Officer and to the Board of Directors

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2026-04-16 12:53

Achieve Life Sciences Announces Up to $354 Million Private Placement

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2026-04-16 12:53

Achieve Life Sciences Announces Up to $354 Million Private Placement

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2026-04-15 12:00

Achieve Life Sciences Announces Operational Progress Including Completion of Technology Transfer to Adare Pharma Solutions

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2026-04-15 12:00

Achieve Life Sciences Announces Operational Progress Including Completion of Technology Transfer to Adare Pharma Solutions

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07392125 Phase 3 Trial Evaluating the Efficacy and Safety of Cytisinicline for Vaping Ce… Phase3 Vaping Cessation Not_Yet_Recruiting 2026-05-15 2027-09-30 ClinicalTrials.gov
NCT06435221 Safety Study of Cytisinicline in Adult Combustible and/or E-cigarette Smokers Phase3 Smoking Cessation Completed 2024-05-28 2025-10-06 ClinicalTrials.gov
NCT05981768 Study to Evaluate Effect of Food on Bioavailability of Single 3 mg Tablet and P… Phase1 Smoking Cessation Completed 2023-08-08 2023-09-21 ClinicalTrials.gov
NCT05631938 Study to Evaluate the Effect of Renal Impairment and Dialysis Treatment on the … Phase1 Renal Impairment Completed 2023-01-10 2023-09-04 ClinicalTrials.gov
NCT05566288 Study to Evaluate Electrocardiographic Effects of Therapeutic & Supratherapeuti… Phase1 Smoking Cessation Completed 2022-10-17 2022-12-23 ClinicalTrials.gov
NCT05431387 A Study of Cytisinicline for Vaping Cessation in Adult Smokers Phase2 Vaping Completed 2022-07-13 2023-02-28 ClinicalTrials.gov
NCT05206370 A Second Study of Cytisinicline for Smoking Cessation in Adult Smokers Phase3 Smoking Cessation Completed 2022-01-20 2023-03-21 ClinicalTrials.gov
NCT04576949 A Study of Cytisinicline for Smoking Cessation in Adult Smokers Phase3 Smoking Cessation Completed 2020-10-13 2021-12-23 ClinicalTrials.gov
NCT03848208 A Single Dose-escalation Study of Cytisine in Adult Smokers Phase1 Smoking Cessation Completed 2019-02-28 2019-09-12 ClinicalTrials.gov
NCT03709823 Trial of Cytisine in Adult Smokers Phase2 Smoking Cessation Completed 2018-11-13 2019-04-23 ClinicalTrials.gov
NCT03509948 A Study in Healthy Smokers to Investigate the Effect of Food on the Bioavailabi… Phase1 Smoking Cessation Completed 2018-04-27 2018-06-12 ClinicalTrials.gov
NCT03303911 A Pharmacokinetic and Pharmacodynamic Evaluation of Cytisine in Healthy Smokers Phase1 Smoking Cessation Terminated 2017-10-06 2018-10-05 ClinicalTrials.gov
NCT03268343 A Study in Healthy Volunteers to Investigate the Effect of Food on the Bioavail… Phase1 Smoking Cessation Completed 2017-08-08 2017-09-01 ClinicalTrials.gov
NCT02423590 Study of Gemcitabine/Carboplatin First-line Chemotherapy +/- Apatorsen in Advan… Phase2 Squamous Cell Lung Cancer Unknown 2014-06-01 2018-06-01 ClinicalTrials.gov
NCT01844817 Phase II Trial Of Gemcitabine Plus Nab-Paclitaxel +/- OGX-427 In Patients With … Phase2 Pancreatic Cancer Completed 2013-09-01 2016-03-01 ClinicalTrials.gov
NCT01829113 Phase II Trial of Carboplatin and Pemetrexed +/- OGX-427 in Untreated Stage IV … Phase2 Non Squamous Non Small Cell Lung Cancer Completed 2013-07-01 2017-04-19 ClinicalTrials.gov
NCT01874561 Thorough QT/QTc (Corrected QT Interval) Study to Evaluate the Effect of Custirs… Phase1 Cardiac Conduction and Repolarization Completed 2013-05-01 2014-01-01 ClinicalTrials.gov
NCT01780545 Phase 2 Study of Docetaxel +/- OGX-427 in Patients With Relapsed or Refractory … Phase2 Bladder Cancer Completed 2013-04-01 2017-10-01 ClinicalTrials.gov
NCT01681433 OGX-427 in Metastatic Castrate-Resistant Prostate Cancer With Prostate-Specific… Phase2 Prostate Cancer Terminated 2012-12-01 2017-06-21 ClinicalTrials.gov
NCT01630733 A Multinational, Randomized, Open-Label Study of Custirsen In Patients With Adv… Phase3 Non-Small Cell Lung Cancer Unknown 2012-09-01 2017-07-01 ClinicalTrials.gov
NCT01578655 Comparison of Cabazitaxel/Prednisone Alone or in Combination With Custirsen for… Phase3 Prostate Cancer Completed 2012-08-01 2016-07-01 ClinicalTrials.gov
NCT01497470 A Clinical Study in Cancer Patients to Investigate the Potential Impact of Cust… Phase1 Cancer Completed 2012-04-01 2013-10-01 ClinicalTrials.gov
NCT01454089 A Phase 2 Study Comparing Chemotherapy in Combination With OGX-427 or Placebo i… Phase2 Urologic Neoplasms Completed 2011-10-01 2014-11-01 ClinicalTrials.gov
NCT01188187 Comparison of Docetaxel/Prednisone to Docetaxel/Prednisone in Combination With … Phase3 Prostate Cancer Completed 2010-11-01 2014-06-01 ClinicalTrials.gov
NCT01120470 OGX-427 in Castration Resistant Prostate Cancer Patients Phase2 Castration Resistant Prostate Cancer Completed 2010-09-01 2014-06-01 ClinicalTrials.gov
NCT01083615 A Study Evaluating the Pain Palliation Benefit of Adding Custirsen to Docetaxel… Phase3 Castrate-Resistant Prostate Cancer Terminated 2010-03-01 2013-03-01 ClinicalTrials.gov
NCT00487786 Safety Study of an Antisense Product in Prostate, Ovarian, NSCL, Breast or Blad… Phase1 Neoplasms Completed 2007-06-01 2011-10-01 ClinicalTrials.gov
NCT00385177 Phase 1 Dose Escalation Study of SN2310 Injectable Emulsion in Patients With Ad… Phase1 Breast Neoplasms Completed 2006-09-01 2009-05-01 ClinicalTrials.gov
NCT00327340 Evaluation of Safety and Feasibility of OGX-011 in Combination With 2nd-line Ch… Phase2 Prostate Cancer Completed 2006-07-01 2010-10-01 ClinicalTrials.gov
NCT00251095 Comparison of Safety and Efficacy of TOCOSOL(R) Paclitaxel Versus Taxol(R) for … Phase3 Breast Neoplasm Terminated 2005-09-01 2007-09-01 ClinicalTrials.gov
NCT00138658 A Study of OGX-011/Gemcitabine/Platinum-Based Regimen in Stage IIIB/IV Non-Smal… Phase1 Non-small Cell Lung Cancer Completed 2004-11-01 2010-03-01 ClinicalTrials.gov
NCT00096668 Evaluation of Safety and Efficacy of TOCOSOL(R) Paclitaxel as Initial Treatment… Phase2 Breast Cancer Completed 2004-10-01 2007-09-01 ClinicalTrials.gov
NCT00077688 TOCOSOL(TM) Paclitaxel in Metastatic or Locally Advanced Unresectable Transitio… Phase2 Bladder Neoplasms Completed 2003-11-01 2007-09-01 ClinicalTrials.gov
NCT00034177 Safety and Efficacy of S-8184 in Treatment of Locally Advanced, Metastatic, or … Phase2 Urologic Neoplasms Completed 2002-04-01 2007-09-01 ClinicalTrials.gov
NCT00034164 Safety and Efficacy of S-8184 in Second Line Treatment of Relapsed Stage IIIB o… Phase2 Carcinoma, Non-Small-Cell Lung Completed 2002-04-01 2007-09-01 ClinicalTrials.gov
NCT00034190 Safety and Efficacy of S-8184 in Second Line Treatment of Stage III or IV Color… Phase2 Colorectal Adenocarcinoma Completed 2002-03-01 2007-09-01 ClinicalTrials.gov
NCT00034151 Safety and Efficacy of S-8184 in Second Line Treatment of Stage III or IV Ovari… Phase2 Ovarian Cancer Completed 2002-03-01 2007-09-01 ClinicalTrials.gov
Total clinical trials: 37
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Behavioral Support BEHAVIORAL Phase PHASE3 Vaping Cessation NOT_YET_RECRUITING NCT07392125
cytisinicline DRUG Phase PHASE1 Renal Impairment COMPLETED NCT05631938
Cytisinicline DRUG Phase PHASE3 Vaping Cessation NOT_YET_RECRUITING NCT07392125
placebo DRUG Phase PHASE1 Smoking Cessation COMPLETED NCT03848208
Behavioral support BEHAVIORAL Phase PHASE2 Vaping COMPLETED NCT05431387
Placebo Comparator DRUG Phase PHASE2 Smoking Cessation COMPLETED NCT03709823
cytisine DRUG Phase PHASE1 Smoking Cessation COMPLETED NCT03848208
Cytisine DRUG Phase PHASE2 Smoking Cessation COMPLETED NCT03709823
Apatorsen (OGX-427) DRUG Phase PHASE2 Squamous Cell Lung Cancer UNKNOWN NCT02423590
Moxifloxacin DRUG Phase PHASE1 Smoking Cessation COMPLETED NCT05566288
Abiraterone Acetate DRUG Phase PHASE2 Prostate Cancer TERMINATED NCT01681433
Custirsen, paclitaxel and carboplatin DRUG Phase PHASE1 Cancer COMPLETED NCT01497470
Carboplatin DRUG Phase PHASE2 Squamous Cell Lung Cancer UNKNOWN NCT02423590
Cisplatin DRUG Phase PHASE2 Urologic Neoplasms COMPLETED NCT01454089
Gemcitabine DRUG Phase PHASE2 Squamous Cell Lung Cancer UNKNOWN NCT02423590
Placebo DRUG Phase PHASE3 Vaping Cessation NOT_YET_RECRUITING NCT07392125
OGX-427 1000 mg DRUG Phase PHASE2 Urologic Neoplasms COMPLETED NCT01454089
OGX-427 600 mg DRUG Phase PHASE2 Urologic Neoplasms COMPLETED NCT01454089
Dexamethasone DRUG Phase PHASE3 Prostate Cancer COMPLETED NCT01188187
Custirsen DRUG Phase PHASE1 Cardiac Conduction and Repolarization COMPLETED NCT01874561
Prednisone DRUG Phase PHASE2 Prostate Cancer TERMINATED NCT01681433
prednisone DRUG Phase PHASE3 Prostate Cancer COMPLETED NCT01578655
cabazitaxel DRUG Phase PHASE3 Prostate Cancer COMPLETED NCT01578655
docetaxel DRUG Phase PHASE3 Castrate-Resistant Prostate Cancer TERMINATED NCT01083615
isotonic, 0.9% sodium chloride DRUG Phase PHASE3 Castrate-Resistant Prostate Cancer TERMINATED NCT01083615
Docetaxel DRUG Phase PHASE2 Bladder Cancer COMPLETED NCT01780545
OGX-427 DRUG Phase PHASE2 Pancreatic Cancer COMPLETED NCT01844817
SN2310 Injectable Emulsion DRUG Phase PHASE1 Breast Neoplasms COMPLETED NCT00385177
custirsen (OGX-011)/docetaxel DRUG Phase PHASE2 Prostate Cancer COMPLETED NCT00327340
custirsen (OGX-011)/mitoxantrone DRUG Phase PHASE2 Prostate Cancer COMPLETED NCT00327340
TOCOSOL Paclitaxel DRUG Phase PHASE3 Breast Neoplasm TERMINATED NCT00251095
Taxol DRUG Phase PHASE3 Breast Neoplasm TERMINATED NCT00251095
custirsen sodium DRUG Phase PHASE3 Prostate Cancer COMPLETED NCT01578655
TOCOSOL(R) Paclitaxel DRUG Phase PHASE2 Breast Cancer COMPLETED NCT00096668
Experimental Arm: TOCOSOL Paclitaxel DRUG Phase PHASE2 Urologic Neoplasms COMPLETED NCT00034177
S-8184 Paclitaxel Injectable Emulsion DRUG Phase PHASE2 Colorectal Adenocarcinoma COMPLETED NCT00034190
Total products: 36