SymbolAEON
NameAEON BIOPHARMA, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address4040 MACARTHUR BLVD,SUITE 260, NEWPORT BEACH, California, 92660, United States
Telephone(949) 354-6499
Fax
Email
Websitehttps://www.aeonbiopharma.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK
Description

AEON Biopharma, Inc. is a bio-pharmaceutical company. The Company is focused on developing ABP-450 (prabotulinumtoxinA) injection for the treatment of debilitating medical conditions with an initial focus on the neurology and gastroenterology markets. ABP-450 contains a 900 kDa botulinum toxin type-A complex produced by the bacterium clostridium botulinum. The active part of the botulinum toxin is the 150 kDa component, and the remaining 750 kDa of the complex is made up of accessory proteins. When injected at therapeutic levels, ABP-450 blocks peripheral acetylcholine release at presynaptic cholinergic nerve terminals by cleaving SNAP-25, a protein integral to the docking and release of acetylcholine from vesicles situated within the nerve endings leading to denervation and relaxation of the muscle. It is also engaged in the Phase II clinical study of ABP-450 for the treatment of cervical dystonia. Cervical dystonia, also known as spasmodic torticollis, is a neurological condition.

Additional info from NASDAQ:
AEON Biopharma, Inc. is a bio-pharmaceutical company. The Company is focused on developing ABP-450 (prabotulinumtoxinA) injection for the treatment of debilitating medical conditions with an initial focus on the neurology and gastroenterology markets. ABP-450 contains a 900 kDa botulinum toxin type-A complex produced by the bacterium clostridium botulinum. The active part of the botulinum toxin is the 150 kDa component, and the remaining 750 kDa of the complex is made up of accessory proteins. When injected at therapeutic levels, ABP-450 blocks peripheral acetylcholine release at presynaptic cholinergic nerve terminals by cleaving SNAP-25, a protein integral to the docking and release of acetylcholine from vesicles situated within the nerve endings leading to denervation and relaxation of the muscle. It is also engaged in the Phase II clinical study of ABP-450 for the treatment of cervical dystonia. Cervical dystonia, also known as spasmodic torticollis, is a neurological condition.

2026-04-03 22:22

Bencich John 🟢 acquired 754.7K shares of AEON Biopharma, Inc. (AEON) Transaction Date: Apr 02, 2026 | Filing ID: 039697

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2026-04-03 20:10

AEON Biopharma Reports Inducement Grants Under NYSE American LLC Company Guide Section 711

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2026-04-03 20:05

(99% Neutral) AEON BIOPHARMA, INC. (AEON) Reports Q1 2026 Financial Results

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2026-04-03 20:05

AEON Biopharma Receives Additional Notice Related to NYSE American Continued Listing Standards

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2026-04-03 19:22

New Form 3 - AEON Biopharma, Inc. <b>Filed:</b> 2026-04-03 <b>AccNo:</b> 0001104659-26-039696 <b>Size:</b> 9 KB

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2026-03-30 21:29

(30% Negative) AEON BIOPHARMA, INC. (AEON) Reports Q1 2026 Financial Results

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2026-03-30 20:05

AEON Biopharma Reports Full Year 2025 Financial Results and Highlights Positive Comparative Analytical Results and FDA Feedback for ABP-450 Biosimilar Program

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2026-03-25 12:00

AEON Biopharma Announces FDA Feedback Following BPD Type 2a Meeting for the ABP-450 Biosimilar Program

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2026-03-09 20:05

AEON Biopharma Appoints John Bencich as Chief Financial Officer

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2026-01-21 21:05

AEON Biopharma Reports BPD Type 2a Meeting with FDA and Shareholder Approval of the November Transactions

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT05016661 Extension Study of ABP-20001 to Evaluate Safety and Efficacy of Repeat Treatmen… Phase2 Migraine Terminated 2021-10-19 2024-08-30 ClinicalTrials.gov
NCT04871451 Extension Study of ABP-19000 to Evaluate Safety and Efficacy of Repeat Treatmen… Phase2 Cervical Dystonia Completed 2021-07-27 2023-07-24 ClinicalTrials.gov
NCT04849988 A Phase 2 Study to Evaluate the Safety and Efficacy of ABP-450 in the Treatment… Phase2 Cervical Dystonia Completed 2021-03-29 2022-07-11 ClinicalTrials.gov
NCT04845178 Investigation of Safety and Efficacy of ABP-450 for Migraine Prevention in Adul… Phase2 Migraine Completed 2021-03-01 2024-08-06 ClinicalTrials.gov
Total clinical trials: 4
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Placebo DRUG Phase PHASE2 Cervical Dystonia COMPLETED NCT04849988
ABP-450 DRUG Phase PHASE2 Migraine TERMINATED NCT05016661
Total products: 2