SymbolAEON
NameAEON BIOPHARMA, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address4040 MACARTHUR BLVD,SUITE 260, NEWPORT BEACH, California, 92660, United States
Telephone(949) 354-6499
Fax
Email
Websitehttps://www.aeonbiopharma.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001837607
Description

AEON Biopharma, Inc. is a bio-pharmaceutical company. The Company is focused on developing ABP-450 (prabotulinumtoxinA) injection for the treatment of debilitating medical conditions with an initial focus on the neurology and gastroenterology markets. ABP-450 contains a 900 kDa botulinum toxin type-A complex produced by the bacterium clostridium botulinum. The active part of the botulinum toxin is the 150 kDa component, and the remaining 750 kDa of the complex is made up of accessory proteins. When injected at therapeutic levels, ABP-450 blocks peripheral acetylcholine release at presynaptic cholinergic nerve terminals by cleaving SNAP-25, a protein integral to the docking and release of acetylcholine from vesicles situated within the nerve endings leading to denervation and relaxation of the muscle. It is also engaged in the Phase II clinical study of ABP-450 for the treatment of cervical dystonia. Cervical dystonia, also known as spasmodic torticollis, is a neurological condition.

Additional info from NASDAQ:
AEON Biopharma, Inc. is a bio-pharmaceutical company. The Company is focused on developing ABP-450 (prabotulinumtoxinA) injection for the treatment of debilitating medical conditions with an initial focus on the neurology and gastroenterology markets. ABP-450 contains a 900 kDa botulinum toxin type-A complex produced by the bacterium clostridium botulinum. The active part of the botulinum toxin is the 150 kDa component, and the remaining 750 kDa of the complex is made up of accessory proteins. When injected at therapeutic levels, ABP-450 blocks peripheral acetylcholine release at presynaptic cholinergic nerve terminals by cleaving SNAP-25, a protein integral to the docking and release of acetylcholine from vesicles situated within the nerve endings leading to denervation and relaxation of the muscle. It is also engaged in the Phase II clinical study of ABP-450 for the treatment of cervical dystonia. Cervical dystonia, also known as spasmodic torticollis, is a neurological condition.

2026-07-15 20:01

(99% Neutral) AEON BIOPHARMA, INC. (AEON) Announces Business Combination

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2026-07-09 11:59

New Form S-1/A - AEON Biopharma, Inc. <b>Filed:</b> 2026-07-09 <b>AccNo:</b> 0001104659-26-082167 <b>Size:</b> 344 KB

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2026-06-22 22:22

Director Thunen Shelley B 🟢 acquired 222.7K shares of AEON Biopharma, Inc. (AEON) Transaction Date: Jun 17, 2026 | Filing ID: 076515

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2026-06-22 22:20

Director PALMISANO ROBERT J 🟢 acquired 222.7K shares of AEON Biopharma, Inc. (AEON) Transaction Date: Jun 17, 2026 | Filing ID: 076513

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2026-06-22 22:19

Director Forth Marc 🟢 acquired 222.7K shares of AEON Biopharma, Inc. (AEON) Transaction Date: Jun 17, 2026 | Filing ID: 076511

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2026-06-22 22:17

Director FISCHER JOST 🟢 acquired 222.7K shares of AEON Biopharma, Inc. (AEON) Transaction Date: Jun 17, 2026 | Filing ID: 076510

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2026-06-22 22:16

Director Carter Eric G 🟢 acquired 222.7K shares of AEON Biopharma, Inc. (AEON) Transaction Date: Jun 17, 2026 | Filing ID: 076509

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2026-06-17 20:05

(99% Neutral) AEON BIOPHARMA, INC. (AEON) Files Form 8-K

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2026-06-04 11:00

AEON Biopharma to Present Data Demonstrating Structural and Functional Comparability of ABP-450 to BOTOX® at the 68th Annual Scientific Meeting of the American Headache Society

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2026-05-14 20:06

(30% Negative) AEON BIOPHARMA, INC. (AEON) Reports Q2 2026 Financial Results

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT05016661 Extension Study of ABP-20001 to Evaluate Safety and Efficacy of Repeat Treatmen… Phase2 Migraine Terminated 2021-10-19 2024-08-30 ClinicalTrials.gov
NCT04871451 Extension Study of ABP-19000 to Evaluate Safety and Efficacy of Repeat Treatmen… Phase2 Cervical Dystonia Completed 2021-07-27 2023-07-24 ClinicalTrials.gov
NCT04849988 A Phase 2 Study to Evaluate the Safety and Efficacy of ABP-450 in the Treatment… Phase2 Cervical Dystonia Completed 2021-03-29 2022-07-11 ClinicalTrials.gov
NCT04845178 Investigation of Safety and Efficacy of ABP-450 for Migraine Prevention in Adul… Phase2 Migraine Completed 2021-03-01 2024-08-06 ClinicalTrials.gov
Total clinical trials: 4
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Placebo Other Phase PHASE2 Cervical Dystonia COMPLETED NCT04849988
ABP-450 Other Phase PHASE2 Cervical Dystonia COMPLETED NCT04849988
ABP-450 Other Phase PHASE2 Cervical Dystonia COMPLETED NCT04871451
Placebo Other Phase PHASE2 Migraine COMPLETED NCT04845178
ABP-450 Other Phase PHASE2 Migraine COMPLETED NCT04845178
ABP-450 Other Phase PHASE2 Migraine TERMINATED NCT05016661
Placebo DRUG Phase PHASE2 Cervical Dystonia COMPLETED NCT04849988
ABP-450 DRUG Phase PHASE2 Migraine TERMINATED NCT05016661
Total products: 8