SymbolALMS
NameALUMIS INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address280 EAST,GRAND AVENUE, SOUTH SAN FRANCISCO, California, 94080, United States
Telephone650-231-6625
Fax
Email
Websitehttps://www.alumis.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK
Description

Alumis mission is to significantly improve the lives of patients by replacing broad immunosuppression with targeted therapies. We are a clinical stage biopharmaceutical company with an initial focus on developing our two Tyrosine Kinase 2 (TYK2) inhibitors: ESK-001, a second-generation inhibitor that we are developing to maximize target inhibition and optimize tolerability, and A-005, a central nervous system (CNS) penetrant molecule. ESK-001 has demonstrated significant therapeutic effect in our Phase 2 program in patients with PsO, which we define as moderate-to-severe plaque psoriasis, and is currently being evaluated in additional Phase 2 clinical trials in patients with systemic lupus erythematosus (SLE) and non-infectious uveitis, for which we expect to report results in 2026 and by the end of 2024, respectively.

Additional info from NASDAQ:
Alumis mission is to significantly improve the lives of patients by replacing broad immunosuppression with targeted therapies. We are a clinical stage biopharmaceutical company with an initial focus on developing our two Tyrosine Kinase 2 (TYK2) inhibitors: ESK-001, a second-generation inhibitor that we are developing to maximize target inhibition and optimize tolerability, and A-005, a central nervous system (CNS) penetrant molecule. ESK-001 has demonstrated significant therapeutic effect in our Phase 2 program in patients with PsO, which we define as moderate-to-severe plaque psoriasis, and is currently being evaluated in additional Phase 2 clinical trials in patients with systemic lupus erythematosus (SLE) and non-infectious uveitis, for which we expect to report results in 2026 and by the end of 2024, respectively.

2026-04-07 17:27

New Form SCHEDULE 13G - ALUMIS INC. <b>Filed:</b> 2026-04-07 <b>AccNo:</b> 0001172661-26-001395 <b>Size:</b> 11 KB

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2026-04-03 19:55

Foresite Labs, LLC 🟡 adjusted position in 496.0K shares of ALUMIS INC. (ALMS) Transaction Date: Apr 01, 2026 | Filing ID: 039611

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2026-04-03 19:53

Director Tananbaum James B. 🟡 adjusted position in 496.0K shares of ALUMIS INC. (ALMS) Transaction Date: Apr 01, 2026 | Filing ID: 039609

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2026-04-03 16:51

New Form SCHEDULE 13D/A - ALUMIS INC. <b>Filed:</b> 2026-04-03 <b>AccNo:</b> 0001104659-26-039608 <b>Size:</b> 54 KB

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2026-03-30 10:06

(90% Positive) ALUMIS INC. (ALMS) Provides Update on Symptoms for Two Phase 3 Trials

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2026-03-28 17:30

Alumis’ Envudeucitinib Delivers Early and Robust Improvements in Skin Clearance, Quality of Life and Psoriasis Symptoms in Two Phase 3 Trials, Underscoring Its Potential as a Leading Oral Therapy for Plaque Psoriasis

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2026-03-19 20:12

(90% Positive) ALUMIS INC. (ALMS) Reports Q1 2026 Financial Results

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2026-03-19 20:05

Alumis Reports Year End 2025 Financial Results and Highlights Recent Achievements

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2026-03-19 18:03

New Form S-3ASR - ALUMIS INC. <b>Filed:</b> 2026-03-19 <b>AccNo:</b> 0001104659-26-032158 <b>Size:</b> 1 MB

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2026-03-18 12:00

Alumis Announces Late-Breaker Oral Presentation of Phase 3 Data for Envudeucitinib in Moderate-to-Severe Plaque Psoriasis at 2026 American Academy of Dermatology Annual Meeting

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT05739435 Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK… Phase2 Plaque Psoriasis Active_Not_Recruiting 2023-01-17 2026-12-30 ClinicalTrials.gov
Total clinical trials: 1
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Placebo DRUG Phase PHASE2 SLE ACTIVE_NOT_RECRUITING NCT05966480
Envudeucitinib DRUG Phase PHASE2 SLE ACTIVE_NOT_RECRUITING NCT05966480
envudeucitinib DRUG Phase PHASE2 Plaque Psoriasis ACTIVE_NOT_RECRUITING NCT05739435
Total products: 3