SymbolANNX
NameANNEXON, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address1400 SIERRA POINT PARKWAY, BLDG C,SUITE 200, BRISBANE, California, 94005, United States
Telephone+1 650 822-5500
Fax
Email
Websitehttps://www.annexonbio.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001528115
Description

Annexon Inc is a clinical-stage biopharmaceutical company developing a pipeline of novel therapies for patients with classical complement-mediated disorders of the body, brain, and eye. Its pipeline is based on its platform technology addressing well-researched classical complement-mediated autoimmune and neurodegenerative disease processes, both of which are triggered by aberrant activation of C1q. Its pipeline of product candidates is designed to block the activity of C1q and the entire classical complement pathway in a broad set of complement-mediated diseases. Annexons product candidates are ANX005, for autoimmune & neurodegenerative disorders; ANX007, for neurodegenerative ophthalmic disorders; and ANX009, for systemic autoimmune diseases.

Additional info from NASDAQ:
Annexon Inc is a clinical-stage biopharmaceutical company developing a pipeline of novel therapies for patients with classical complement-mediated disorders of the body, brain, and eye. Its pipeline is based on its platform technology addressing well-researched classical complement-mediated autoimmune and neurodegenerative disease processes, both of which are triggered by aberrant activation of C1q. Its pipeline of product candidates is designed to block the activity of C1q and the entire classical complement pathway in a broad set of complement-mediated diseases. Annexons product candidates are ANX005, for autoimmune & neurodegenerative disorders; ANX007, for neurodegenerative ophthalmic disorders; and ANX009, for systemic autoimmune diseases.

2026-07-16 20:05

Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

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2026-07-15 20:19

📋 WIGGANS THOMAS G (Ex-Director) plans to sell 2K shares of Annexon, Inc. (at $6.32 each, total $13K) Filed: Jul 15, 2026 | ID: 005238

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2026-06-16 20:05

Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

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2026-06-15 20:15

Waddill William D. 🟢 acquired 65.0K shares (1 derivative) of Annexon, Inc. (ANNX) at $4.70 Transaction Date: Jun 11, 2026 | Filing ID: 000001

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2026-06-15 20:15

Satter Muneer A 🟢 acquired 65.0K shares (1 derivative) of Annexon, Inc. (ANNX) at $4.70 Transaction Date: Jun 11, 2026 | Filing ID: 000002

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2026-06-15 20:15

JONES WILLIAM A JR 🟢 acquired 65.0K shares (1 derivative) of Annexon, Inc. (ANNX) at $4.70 Transaction Date: Jun 11, 2026 | Filing ID: 000001

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2026-06-15 20:15

Cockroft Bettina M. 🟢 acquired 65.0K shares (1 derivative) of Annexon, Inc. (ANNX) at $4.70 Transaction Date: Jun 11, 2026 | Filing ID: 000001

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2026-06-15 20:15

Choi Jung 🟢 acquired 65.0K shares (1 derivative) of Annexon, Inc. (ANNX) at $4.70 Transaction Date: Jun 11, 2026 | Filing ID: 000001

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2026-06-15 20:15

Carson William H. 🟢 acquired 65.0K shares (1 derivative) of Annexon, Inc. (ANNX) at $4.70 Transaction Date: Jun 11, 2026 | Filing ID: 000005

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2026-06-15 20:15

Yednock Ted 🟡 adjusted position in 0 shares (1 derivative) of Annexon, Inc. (ANNX) at $1.85 Transaction Date: Jun 11, 2026 | Filing ID: 000004

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07020819 An Open Label Clinical Study to Evaluate Tanruprubart (Also Commonly Known as A… Phase3 Guillain-Barre Syndrome Recruiting 2025-09-12 2028-06-30 ClinicalTrials.gov
NCT06510816 A Study Investigating the Efficacy and Safety of Intravitreal (IVT) Injections … Phase3 Geographic Atrophy Active_Not_Recruiting 2024-07-30 2027-07-31 ClinicalTrials.gov
NCT05780515 A Study of ANX009 in Adult Participants With Lupus Nephritis Phase1 Lupus Nephritis Completed 2022-08-09 2023-10-31 ClinicalTrials.gov
NCT05521269 Dose Study of ANX1502 in Healthy Volunteers Phase1 Healthy Completed 2022-06-27 2024-11-19 ClinicalTrials.gov
NCT05288881 Single Ascending Dose Study of ANX105 Phase1 Healthy Completed 2022-02-28 2023-06-19 ClinicalTrials.gov
NCT04691570 Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ANX005 in Partic… Phase2 Warm Autoimmune Hemolytic Anemia (wAIHA) Completed 2021-11-10 2023-01-17 ClinicalTrials.gov
NCT04656561 A Study Investigating the Efficacy and Safety of Intravitreal Injections of ANX… Phase2 Geographic Atrophy Completed 2021-02-26 2023-09-13 ClinicalTrials.gov
NCT04569435 Study of ANX005 in Adults With Amyotrophic Lateral Sclerosis (ALS) Phase2 Amyotrophic Lateral Sclerosis Completed 2021-01-15 2024-04-23 ClinicalTrials.gov
NCT04701164 Efficacy and Safety of ANX005 in Subjects With Guillain-Barré Syndrome Phase3 Guillain-Barre Syndrome Completed 2020-12-17 2024-04-20 ClinicalTrials.gov
NCT04535752 A Single and Multiple Ascending Dose Study of ANX009 in Normal Healthy Voluntee… Phase1 Safety and Tolerability in Healthy Volunteers Completed 2020-10-30 2021-06-26 ClinicalTrials.gov
NCT04514367 An Open Label Study of ANX005 in Subjects With, or at Risk for, Manifest Huntin… Phase2 Huntington Disease Completed 2020-08-17 2022-01-28 ClinicalTrials.gov
NCT04035135 A Clinical Study of ANX005 and IVIG in Subjects With Guillain Barré Syndrome (G… Phase1 Guillain-Barré Syndrome Completed 2020-01-29 2021-05-19 ClinicalTrials.gov
NCT04188015 Study of ANX007 in Participants With Primary Open-angle Glaucoma Phase1 Open Angle Glaucoma Completed 2018-07-25 2019-06-03 ClinicalTrials.gov
NCT03488550 Single-dose Study of ANX007 in Participants With Primary Open-angle Glaucoma Phase1 Open-angle Glaucoma Completed 2018-03-23 2018-08-03 ClinicalTrials.gov
NCT03010046 Single Dose Study of ANX005 in Healthy Volunteers Phase1 Safety and Tolerability in Healthy Volunteers Terminated 2016-12-01 2018-06-01 ClinicalTrials.gov
NCT07424235 Evaluating the Relationship Between Function and Structure in ARCHER II-like Po… Age Related Macular Degeneration (AMD) Completed 2015-01-01 2024-12-01 ClinicalTrials.gov
Total clinical trials: 16
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
ANX005 Other Phase PHASE2 Warm Autoimmune Hemolytic Anemia (wAIHA) COMPLETED NCT04691570
Tanruprubart Other Phase PHASE3 Guillain-Barre Syndrome RECRUITING NCT07020819
Sham Administration Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Sham Administration Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Sham Administration Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Sham Administration Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Sham Administration Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Sham Administration Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Sham Administration Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Sham Administration Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Sham Administration Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Sham Administration Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Sham Procedure Procedure Phase PHASE1 Open Angle Glaucoma COMPLETED NCT04188015
5.0mg ANX007 Other Phase PHASE1 Open Angle Glaucoma COMPLETED NCT04188015
2.5mg ANX007 Other Phase PHASE1 Open Angle Glaucoma COMPLETED NCT04188015
ANX007 Other Phase PHASE1 Open-angle Glaucoma COMPLETED NCT03488550
Placebos Other Phase PHASE1 Safety and Tolerability in Healthy Volunteers TERMINATED NCT03010046
IVIg Other Phase PHASE1 Safety and Tolerability in Healthy Volunteers TERMINATED NCT03010046
ANX005 Other Phase PHASE1 Safety and Tolerability in Healthy Volunteers TERMINATED NCT03010046
Intravenous immunoglobulin Other Phase PHASE1 Guillain-Barré Syndrome COMPLETED NCT04035135
ANX005 Other Phase PHASE1 Guillain-Barré Syndrome COMPLETED NCT04035135
Placebo Other Phase PHASE1 Safety and Tolerability in Healthy Volunteers COMPLETED NCT04535752
ANX009 Other Phase PHASE1 Safety and Tolerability in Healthy Volunteers COMPLETED NCT04535752
ANX005 Other Phase PHASE2 Huntington Disease COMPLETED NCT04514367
ANX005 Other Phase PHASE2 Warm Autoimmune Hemolytic Anemia (wAIHA) COMPLETED NCT04691570
Placebo Other Phase PHASE1 Healthy COMPLETED NCT05288881
ANX105 Other Phase PHASE1 Healthy COMPLETED NCT05288881
Sham comparator Other Phase PHASE2 Geographic Atrophy COMPLETED NCT04656561
ANX007 Other Phase PHASE2 Geographic Atrophy COMPLETED NCT04656561
ANX009 Other Phase PHASE1 Lupus Nephritis COMPLETED NCT05780515
Placebo Other Phase PHASE1 Healthy COMPLETED NCT05521269
ANX1502 Other Phase PHASE1 Healthy COMPLETED NCT05521269
ANX005 Other Phase PHASE2 Amyotrophic Lateral Sclerosis COMPLETED NCT04569435
Placebo Other Phase PHASE3 Guillain-Barre Syndrome COMPLETED NCT04701164
ANX005 Other Phase PHASE3 Guillain-Barre Syndrome COMPLETED NCT04701164
Sham Administration Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument Other Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Tanruprubart Other Phase PHASE3 Guillain-Barre Syndrome RECRUITING NCT07020819
Tanruprubart DRUG Phase PHASE3 Guillain-Barre Syndrome RECRUITING NCT07020819
Sham Administration OTHER Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
Vonaprument DRUG Phase PHASE3 Geographic Atrophy ACTIVE_NOT_RECRUITING NCT06510816
ANX1502 DRUG Phase PHASE1 Healthy COMPLETED NCT05521269
ANX105 BIOLOGICAL Phase PHASE1 Healthy COMPLETED NCT05288881
Sham comparator OTHER Phase PHASE2 Geographic Atrophy COMPLETED NCT04656561
Placebo DRUG Phase PHASE1 Healthy COMPLETED NCT05521269
ANX009 BIOLOGICAL Phase PHASE1 Lupus Nephritis COMPLETED NCT05780515
Sham Procedure OTHER Phase PHASE1 Open Angle Glaucoma COMPLETED NCT04188015
5.0mg ANX007 BIOLOGICAL Phase PHASE1 Open Angle Glaucoma COMPLETED NCT04188015
2.5mg ANX007 BIOLOGICAL Phase PHASE1 Open Angle Glaucoma COMPLETED NCT04188015
Intravenous immunoglobulin DRUG Phase PHASE1 Guillain-Barré Syndrome COMPLETED NCT04035135
ANX007 DRUG Phase PHASE2 Geographic Atrophy COMPLETED NCT04656561
Placebos DRUG Phase PHASE1 Safety and Tolerability in Healthy Volunteers TERMINATED NCT03010046
IVIg DRUG Phase PHASE1 Safety and Tolerability in Healthy Volunteers TERMINATED NCT03010046
ANX005 DRUG Phase PHASE3 Guillain-Barre Syndrome COMPLETED NCT04701164
Total products: 64