SymbolCALC
NameCALCIMEDICA, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address505 COAST BOULEVARD SOUTH,SUITE 307, LA JOLLA, California, 92037, United States
Telephone858-952-5500
Fax
Email
Websitehttps://www.calcimedica.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK
Description

CalciMedica, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing therapies for life-threatening inflammatory diseases with high unmet needs. Its technology targets the inhibition of Calcium Release-Activated Calcium (CRAC) channels designed to modulate the immune response and protect against tissue cell injury, with the potential to provide therapeutic benefits in life-threatening inflammatory diseases. CRAC channels serve to replenish calcium levels in the endoplasmic reticulum (ER) and provide calcium for cellular signaling events. Its lead product candidate, Auxora, is an intravenous-formulated, small molecule CRAC channel inhibitor. Auxora has the capability to modulate the immune response and protect against tissue cell injury, addressing inflammatory diseases, such as acute pancreatitis (AP), asparaginase-associated acute pancreatitis (AAP), acute kidney injury (AKI), and acute hypoxemic respiratory failure.

Additional info from NASDAQ:
CalciMedica, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing therapies for life-threatening inflammatory diseases with high unmet needs. Its technology targets the inhibition of Calcium Release-Activated Calcium (CRAC) channels designed to modulate the immune response and protect against tissue cell injury, with the potential to provide therapeutic benefits in life-threatening inflammatory diseases. CRAC channels serve to replenish calcium levels in the endoplasmic reticulum (ER) and provide calcium for cellular signaling events. Its lead product candidate, Auxora, is an intravenous-formulated, small molecule CRAC channel inhibitor. Auxora has the capability to modulate the immune response and protect against tissue cell injury, addressing inflammatory diseases, such as acute pancreatitis (AP), asparaginase-associated acute pancreatitis (AAP), acute kidney injury (AKI), and acute hypoxemic respiratory failure.

2026-04-08 01:50

Bardin Stephen 🟢 acquired 67.7K shares (1 derivative) of CalciMedica, Inc. (CALC) at $0.58 Transaction Date: Apr 05, 2026 | Filing ID: 000002

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2026-04-08 01:50

Hebbar Sudarshan 🟢 acquired 91.2K shares (1 derivative) of CalciMedica, Inc. (CALC) at $0.58 Transaction Date: Apr 05, 2026 | Filing ID: 000002

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2026-04-08 01:50

Roberts Eric W 🟢 acquired 83.4K shares (1 derivative) of CalciMedica, Inc. (CALC) at $0.58 Transaction Date: Apr 05, 2026 | Filing ID: 000002

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2026-04-08 01:50

Dunn Michael J. 🟢 acquired 65.1K shares (1 derivative) of CalciMedica, Inc. (CALC) at $0.58 Transaction Date: Apr 05, 2026 | Filing ID: 000002

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2026-04-08 01:50

Stauderman Kenneth A. 🟢 acquired 65.1K shares (1 derivative) of CalciMedica, Inc. (CALC) at $0.58 Transaction Date: Apr 05, 2026 | Filing ID: 000002

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2026-04-08 01:50

Leheny A. Rachel 🟢 acquired 148.5K shares (1 derivative) of CalciMedica, Inc. (CALC) at $0.58 Transaction Date: Apr 05, 2026 | Filing ID: 000002

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2026-03-21 02:28

NASDAQ traded attribute type Financial_Status was changed. Previous value: Normal. New value: Deficient.

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2026-03-21 02:28

CALC attributes changed: Attr: Fin_status N -> D;

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2026-03-21 01:50

NASDAQ symbol attribute type Financial_Status was changed. Previous value: Normal. New value: Deficient.

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2026-03-03 18:55

New Form S-3 - CalciMedica, Inc. <b>Filed:</b> 2026-03-03 <b>AccNo:</b> 0001193125-26-088562 <b>Size:</b> 1 MB

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT06374797 A Study of Auxora in Patients With AKI and Injurious Lung "Crosstalk" Phase2 Acute Kidney Injury Active_Not_Recruiting 2024-07-01 2026-04-01 ClinicalTrials.gov
NCT05171920 A Placebo-Controlled Study of Auxora for the Extended Treatment of High- Risk P… Phase2 Pneumonia Withdrawn 2022-01-24 2022-07-01 ClinicalTrials.gov
NCT04681066 A Study of Auxora in Patients With Acute Pancreatitis and Accompanying SIRS Phase2 Acute Pancreatitis Completed 2021-03-24 2024-05-15 ClinicalTrials.gov
NCT04661540 A Study of Auxora in Patients With Critical COVID-19 Pneumonia Phase2 Pneumonia Terminated 2021-03-02 2021-12-21 ClinicalTrials.gov
NCT04195347 Study of CM4620 to Reduce the Severity of Pancreatitis Due to Asparaginase Phase1 Acute Pancreatitis Recruiting 2020-09-04 2029-01-01 ClinicalTrials.gov
NCT04345614 A Study of Auxora in Patients With Severe COVID-19 Pneumonia Phase2 Pneumonia Completed 2020-04-08 2021-07-30 ClinicalTrials.gov
NCT03709342 A PK/PD Study of CM4620-IE in Patients With Acute Pancreatitis Phase2 Acute Pancreatitis Completed 2019-01-06 2019-06-07 ClinicalTrials.gov
NCT03401190 CM4620 Injectable Emulsion Versus Supportive Care in Patients With Acute Pancre… Phase2 Acute Pancreatitis Completed 2018-03-12 2019-04-30 ClinicalTrials.gov
Total clinical trials: 8
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Placebo Other Phase PHASE2 Pneumonia WITHDRAWN NCT05171920
Auxora Other Phase PHASE2 Pneumonia WITHDRAWN NCT05171920
CM4620-IE Other Phase PHASE2 Acute Pancreatitis COMPLETED NCT03709342
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
Placebo Other Phase PHASE2 Acute Pancreatitis COMPLETED NCT04681066
CM-4620 Injectable Emulsion or CM-4620-IE Other Phase PHASE2 Acute Pancreatitis COMPLETED NCT04681066
Placebo Other Phase PHASE2 Acute Kidney Injury ACTIVE_NOT_RECRUITING NCT06374797
Auxora Other Phase PHASE2 Acute Kidney Injury ACTIVE_NOT_RECRUITING NCT06374797
Placebo Other Phase PHASE2 Pneumonia TERMINATED NCT04661540
CM4620-IE (Injectable Emulsion) Other Phase PHASE2 Pneumonia TERMINATED NCT04661540
Placebo (Part 2) Other Phase PHASE2 Pneumonia COMPLETED NCT04345614
Auxora (Part 2) Other Phase PHASE2 Pneumonia COMPLETED NCT04345614
Standard of Care (Part 1) Other Phase PHASE2 Pneumonia COMPLETED NCT04345614
Auxora (Part 1) Other Phase PHASE2 Pneumonia COMPLETED NCT04345614
CM4620 Injectable Emulsion (High Dose) Other Phase PHASE2 Acute Pancreatitis COMPLETED NCT03401190
CM4620 Injectable Emulsion (Low Dose) Other Phase PHASE2 Acute Pancreatitis COMPLETED NCT03401190
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620 Other Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
Auxora DRUG Phase PHASE2 Acute Kidney Injury ACTIVE_NOT_RECRUITING NCT06374797
CM-4620 Injectable Emulsion or CM-4620-IE DRUG Phase PHASE2 Acute Pancreatitis COMPLETED NCT04681066
Placebo DRUG Phase PHASE2 Acute Kidney Injury ACTIVE_NOT_RECRUITING NCT06374797
CM4620-IE (Injectable Emulsion) DRUG Phase PHASE2 Pneumonia TERMINATED NCT04661540
Placebo (Part 2) DRUG Phase PHASE2 Pneumonia COMPLETED NCT04345614
Auxora (Part 2) DRUG Phase PHASE2 Pneumonia COMPLETED NCT04345614
Standard of Care (Part 1) DRUG Phase PHASE2 Pneumonia COMPLETED NCT04345614
Auxora (Part 1) DRUG Phase PHASE2 Pneumonia COMPLETED NCT04345614
CM4620 DRUG Phase PHASE1 Acute Pancreatitis RECRUITING NCT04195347
CM4620-IE DRUG Phase PHASE2 Acute Pancreatitis COMPLETED NCT03709342
CM4620 Injectable Emulsion (High Dose) DRUG Phase PHASE2 Acute Pancreatitis COMPLETED NCT03401190
CM4620 Injectable Emulsion (Low Dose) DRUG Phase PHASE2 Acute Pancreatitis COMPLETED NCT03401190
Total products: 40