SymbolCGEM
NameCULLINAN THERAPEUTICS, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Biological Products (No Diagnostic Substances)
AddressONE MAIN STREET,SUITE 520, CAMBRIDGE, Massachusetts, 02142, United States
Telephone+1 617 410-4650
Fax
Email
Websitehttps://cullinantherapeutics.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001789972
Description

Cullinan Therapeutics, Inc., formerly Cullinan Oncology, Inc., is a biopharmaceutical company focused on developing modality-agnostic targeted therapies. It has a portfolio of clinical-stage assets that inhibit key drivers of disease or harness the immune system to eliminate diseased cells in both oncology and autoimmune diseases. Its pipeline includes CLN-619, CLN-978, Zipalertinib (CLN-081/TAS6417), CLN-049, CLN-418, and CLN-617. Its lead unpartnered program, CLN-619, is a humanized lgG1 monoclonal antibody (mAb) that binds to the stress induced ligands MICA and MICB (MICA/B), which are expressed on a variety of solid tumors and hematologic malignancies. CLN-978 is a novel, highly potent, half-life extended CD19xCD3 bispecific T cell engager construct. CLN-081/TAS6417 is a novel, orally available, covalent inhibitor of mutant epidermal growth factor receptor (EGFR). CLN-049 is a FLT3xCD3 T cell engaging bispecific antibody. CLN-418 is a B7H4 x 4-1BB bispecific immune activator.

Additional info from NASDAQ:
Cullinan Therapeutics, Inc., formerly Cullinan Oncology, Inc., is a biopharmaceutical company focused on developing modality-agnostic targeted therapies. It has a portfolio of clinical-stage assets that inhibit key drivers of disease or harness the immune system to eliminate diseased cells in both oncology and autoimmune diseases. Its pipeline includes CLN-619, CLN-978, Zipalertinib (CLN-081/TAS6417), CLN-049, CLN-418, and CLN-617. Its lead unpartnered program, CLN-619, is a humanized lgG1 monoclonal antibody (mAb) that binds to the stress induced ligands MICA and MICB (MICA/B), which are expressed on a variety of solid tumors and hematologic malignancies. CLN-978 is a novel, highly potent, half-life extended CD19xCD3 bispecific T cell engager construct. CLN-081/TAS6417 is a novel, orally available, covalent inhibitor of mutant epidermal growth factor receptor (EGFR). CLN-049 is a FLT3xCD3 T cell engaging bispecific antibody. CLN-418 is a B7H4 x 4-1BB bispecific immune activator.

2026-09-14 11:29

(90% Positive) CULLINAN THERAPEUTICS, INC. (CGEM) Provides Update on patients for epidermal

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2026-09-14 11:00

Cullinan Therapeutics to Host Virtual Analyst and Investor Event Today to Feature Zipalertinib Plus Chemotherapy Phase 3 REZILIENT3 Data Presented at the IASLC 2026 World Conference on Lung Cancer

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2026-09-13 23:15

Zipalertinib Plus Chemotherapy Demonstrates 6-Month Median Progression-Free Survival Benefit in REZILIENT3 Phase 3 Trial in First-Line EGFR Exon 20 Insertion Mutation Non-Small Cell Lung Cancer

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2026-09-10 17:00

Cullinan Therapeutics to Host Virtual Analyst and Investor Event to Showcase Zipalertinib Plus Chemotherapy Phase 3 REZILIENT3 Data Presented at the IASLC 2026 World Conference on Lung Cancer

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2026-09-10 13:22

Michaelson Jennifer 🟡 adjusted position in 8.0K shares (1 derivative) of Cullinan Therapeutics, Inc. (CGEM) at $21.57 Transaction Date: Sep 08, 2026 | Filing ID: 387381

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2026-09-08 20:25

📋 JENNIFER MICHAELSON (Officer) plans to sell 8K shares of CULLINAN THERAPEUTICS, INC. (at $22.09 each, total $177K) Filed: Sep 08, 2026 | ID: 009190

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2026-08-19 16:03

Zipalertinib Plus Chemotherapy First-Line Phase 3 REZILIENT3 Trial Data Selected for Presidential Symposium Presentation at the IASLC 2026 World Conference on Lung Cancer

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2026-08-14 21:00

Michaelson Jennifer 🟡 adjusted position in 30.0K shares (1 derivative) of Cullinan Therapeutics, Inc. (CGEM) at $20.26 Transaction Date: Aug 13, 2026 | Filing ID: 352523

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2026-08-14 17:11

New Form SCHEDULE 13G/A - Cullinan Therapeutics, Inc. <b>Filed:</b> 2026-08-14 <b>AccNo:</b> 0000921895-26-002166 <b>Size:</b> 25 KB

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2026-08-12 23:30

Zipalertinib Plus Chemotherapy Meets Primary Endpoint of Progression-Free Survival in Planned Interim Analysis of Phase 3 REZILIENT3 Trial in First-Line EGFR Exon 20 Insertion Mutation Non-Small Cell Lung Cancer

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07738822 A Phase 1b/2a Study of Velinotamig in Adults With Relapsed/Refractory ITP and w… Phase1 Immune Thrombocytopenia (ITP) Not_Yet_Recruiting 2026-12-01 2031-01-01 ClinicalTrials.gov
NCT07722767 A Phase 1b Study of CLN-049 in Combination With Azacitidine and Venetoclax in A… Phase1 AML (Acute Myeloid Leukemia) Not_Yet_Recruiting 2026-10-15 2030-08-31 ClinicalTrials.gov
NCT07041099 A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager,… Phase1 Sjögren Recruiting 2025-10-01 2029-03-15 ClinicalTrials.gov
NCT06994143 A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager,… Phase1 Rheumatoid Arthritis (RA Recruiting 2025-05-19 2028-12-30 ClinicalTrials.gov
NCT06613360 A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager,… Phase1 SLE Recruiting 2025-01-21 2027-12-01 ClinicalTrials.gov
NCT06381141 A Study of CLN-619 (Anti-MICA/MICB Antibody) in Patients With Relapsed and Refr… Phase1 Multiple Myeloma Active_Not_Recruiting 2024-09-03 2027-03-01 ClinicalTrials.gov
NCT06035744 CLN-617 Alone and in Combination With Pembrolizumab in Patients With Advanced S… Phase1 Advanced Solid Tumor Terminated 2023-12-12 2026-06-16 ClinicalTrials.gov
NCT05879744 A Study of CLN-978 in Patients With Relapsed or Refractory (R/R) B Cell Non-Hod… Phase1 NHL Active_Not_Recruiting 2023-05-31 2027-04-01 ClinicalTrials.gov
NCT05143996 CLN-049 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML) or My… Phase1 Relapsed/Refractory Acute Myeloid Leukemia (AML) Recruiting 2021-11-18 2027-06-01 ClinicalTrials.gov
NCT05117476 A Study of CLN-619 Alone and in Combination With Pembrolizumab in Advanced Soli… Phase1 Advanced Solid Tumor Active_Not_Recruiting 2021-10-29 2026-06-01 ClinicalTrials.gov
NCT04036682 A Phase 1/2 Trial of CLN-081 in Patients With Non-Small Cell Lung Cancer Phase1 Non Small Cell Lung Cancer Active_Not_Recruiting 2019-10-31 2028-03-31 ClinicalTrials.gov
NCT03682055 Phase 1/2a Study of VK-2019 in Patients With Epstein-Barr Virus (EBV)-Positive … Phase1 Nasopharyngeal Carcinoma Terminated 2019-04-04 2020-08-08 ClinicalTrials.gov
Total clinical trials: 12
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
CLN-978 Other Phase PHASE1 Sjögren RECRUITING NCT07041099
Velinotamig specified dose on specified days. Other Phase PHASE1 Immune Thrombocytopenia (ITP) NOT_YET_RECRUITING NCT07738822
Venetoclax Other Phase PHASE1 AML (Acute Myeloid Leukemia) NOT_YET_RECRUITING NCT07722767
Azacitidine Other Phase PHASE1 AML (Acute Myeloid Leukemia) NOT_YET_RECRUITING NCT07722767
CLN-049 Other Phase PHASE1 AML (Acute Myeloid Leukemia) NOT_YET_RECRUITING NCT07722767
Pembrolizumab Other Phase PHASE1 Advanced Solid Tumor TERMINATED NCT06035744
CLN-617 Other Phase PHASE1 Advanced Solid Tumor TERMINATED NCT06035744
CLN-081 Other Phase PHASE1 Non Small Cell Lung Cancer ACTIVE_NOT_RECRUITING NCT04036682
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-978 Other Phase PHASE1 Rheumatoid Arthritis (RA RECRUITING NCT06994143
CLN-978 Other Phase PHASE1 Rheumatoid Arthritis (RA RECRUITING NCT06994143
CLN-978 Other Phase PHASE1 Rheumatoid Arthritis (RA RECRUITING NCT06994143
CLN-978 Other Phase PHASE1 Rheumatoid Arthritis (RA RECRUITING NCT06994143
CLN-978 Other Phase PHASE1 Rheumatoid Arthritis (RA RECRUITING NCT06994143
CLN-978 Other Phase PHASE1 Rheumatoid Arthritis (RA RECRUITING NCT06994143
CLN-978 Other Phase PHASE1 Rheumatoid Arthritis (RA RECRUITING NCT06994143
CLN-978 Other Phase PHASE1 Rheumatoid Arthritis (RA RECRUITING NCT06994143
VK-2019 Other Phase PHASE1 Nasopharyngeal Carcinoma TERMINATED NCT03682055
CLN-978 Other Phase PHASE1 NHL ACTIVE_NOT_RECRUITING NCT05879744
Pembrolizumab Other Phase PHASE1 Advanced Solid Tumor RECRUITING NCT06035744
CLN-617 Other Phase PHASE1 Advanced Solid Tumor RECRUITING NCT06035744
CLN-081 Other Phase PHASE1 Non Small Cell Lung Cancer ACTIVE_NOT_RECRUITING NCT04036682
CLN-978 Other Phase PHASE1 Rheumatoid Arthritis (RA RECRUITING NCT06994143
CLN-619 Other Phase PHASE1 Multiple Myeloma ACTIVE_NOT_RECRUITING NCT06381141
CLN-978 Other Phase PHASE1 Sjögren RECRUITING NCT07041099
Datopotamab deruxtecan-dlnk (Dato-DXd) Other Phase PHASE1 Advanced Solid Tumor ACTIVE_NOT_RECRUITING NCT05117476
pemetrexed Other Phase PHASE1 Advanced Solid Tumor ACTIVE_NOT_RECRUITING NCT05117476
Carboplatin AUC 6 Other Phase PHASE1 Advanced Solid Tumor ACTIVE_NOT_RECRUITING NCT05117476
Paclitaxel Other Phase PHASE1 Advanced Solid Tumor ACTIVE_NOT_RECRUITING NCT05117476
Pembrolizumab Other Phase PHASE1 Advanced Solid Tumor ACTIVE_NOT_RECRUITING NCT05117476
CLN-619 Other Phase PHASE1 Advanced Solid Tumor ACTIVE_NOT_RECRUITING NCT05117476
CLN-049 Other Phase PHASE1 Relapsed/Refractory Acute Myeloid Leukemia (AML) RECRUITING NCT05143996
CLN-978 Other Phase PHASE1 SLE RECRUITING NCT06613360
CLN-617 DRUG Phase PHASE1 Advanced Solid Tumor RECRUITING NCT06035744
CLN-978 DRUG Phase PHASE1 Sjögren RECRUITING NCT07041099
CLN-049 DRUG Phase PHASE1 Relapsed/Refractory Acute Myeloid Leukemia (AML) RECRUITING NCT05143996
Datopotamab deruxtecan-dlnk (Dato-DXd) DRUG Phase PHASE1 Advanced Solid Tumor ACTIVE_NOT_RECRUITING NCT05117476
pemetrexed DRUG Phase PHASE1 Advanced Solid Tumor ACTIVE_NOT_RECRUITING NCT05117476
Carboplatin AUC 6 DRUG Phase PHASE1 Advanced Solid Tumor ACTIVE_NOT_RECRUITING NCT05117476
Paclitaxel DRUG Phase PHASE1 Advanced Solid Tumor ACTIVE_NOT_RECRUITING NCT05117476
Pembrolizumab DRUG Phase PHASE1 Advanced Solid Tumor RECRUITING NCT06035744
CLN-619 DRUG Phase PHASE1 Multiple Myeloma ACTIVE_NOT_RECRUITING NCT06381141
CLN-081 DRUG Phase PHASE1 Non Small Cell Lung Cancer ACTIVE_NOT_RECRUITING NCT04036682
VK-2019 DRUG Phase PHASE1 Nasopharyngeal Carcinoma TERMINATED NCT03682055
Total products: 58