SymbolGH
NameGUARDANT HEALTH, INC.
SectorHEALTH CARE
RegionNorth America
IndustryMedical Specialities
Address505 PENOBSCOT DRIVE, REDWOOD CITY, California, 94063, United States
Telephone+1 855 698-8887
Fax
Email
Websitehttps://www.guardanthealth.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001576280
Description

Guardant Health, based in Redwood City, California, provides cancer blood tests and analytics for clinical and research use, and the firm maintains research partnerships with large biopharmaceutical companies. The company offers Guardant 360, a blood-based (liquid biopsy) test for treatment selection in advanced stage cancer, and Guardant Omni, a broader gene panel for immuno-oncology research. The companys pipeline includes Guardant Reveal (formerly Lunar-1), for cancer recurrence detection in survivors, and Lunar-2, a liquid biopsy for early detection of cancer in higher-risk individuals, with an initial focus on colorectal cancer. Additionally, Guardant offers research development services. The United States accounts for 90% of total revenue, and other markets the remaining 10%.

Additional info from NASDAQ:
Guardant Health, based in Redwood City, California, provides cancer blood tests and analytics for clinical and research use, and the firm maintains research partnerships with large biopharmaceutical companies. The company offers Guardant 360, a blood-based (liquid biopsy) test for treatment selection in advanced stage cancer, and Guardant Omni, a broader gene panel for immuno-oncology research. The companys pipeline includes Guardant Reveal (formerly Lunar-1), for cancer recurrence detection in survivors, and Lunar-2, a liquid biopsy for early detection of cancer in higher-risk individuals, with an initial focus on colorectal cancer. Additionally, Guardant offers research development services. The United States accounts for 90% of total revenue, and other markets the remaining 10%.

2026-06-22 21:55

Director Tariq Musa 🟡 adjusted position in 2.7K shares (2 derivative) of Guardant Health, Inc. (GH) Transaction Date: Jun 17, 2026 | Filing ID: 000016

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2026-06-22 21:54

Director POTTER MYRTLE S 🟡 adjusted position in 2.7K shares (2 derivative) of Guardant Health, Inc. (GH) Transaction Date: Jun 17, 2026 | Filing ID: 000002

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2026-06-22 21:54

Director MIGNONE ROBERTO 🟡 adjusted position in 2.7K shares (2 derivative) of Guardant Health, Inc. (GH) Transaction Date: Jun 17, 2026 | Filing ID: 000010

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2026-06-22 21:53

Director Krognes Steve E. 🟡 adjusted position in 2.7K shares (2 derivative) of Guardant Health, Inc. (GH) Transaction Date: Jun 17, 2026 | Filing ID: 000020

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2026-06-22 21:53

Director Joyce Meghan V. 🟡 adjusted position in 0 shares (1 derivative) of Guardant Health, Inc. (GH) Transaction Date: Jun 17, 2026 | Filing ID: 000005

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2026-06-22 21:52

Director Hidalgo Medina Manuel 🟡 adjusted position in 2.7K shares (3 derivative) of Guardant Health, Inc. (GH) Transaction Date: Jun 17, 2026 | Filing ID: 000020

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2026-06-22 21:51

Director Gadde Vijaya 🟡 adjusted position in 2.7K shares (2 derivative) of Guardant Health, Inc. (GH) Transaction Date: Jun 17, 2026 | Filing ID: 000002

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2026-06-22 21:51

Director CLARK IAN T 🟡 adjusted position in 2.7K shares (2 derivative) of Guardant Health, Inc. (GH) Transaction Date: Jun 17, 2026 | Filing ID: 000004

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2026-06-22 21:50

Director Azar Alex M II 🟢 acquired 2.7K shares (1 derivative) of Guardant Health, Inc. (GH) Transaction Date: Jun 17, 2026 | Filing ID: 000002

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2026-06-22 20:09

📋 POTTER MYRTLE S (Director) plans to sell 2K shares of Guardant Health, Inc. (at $131.16 each, total $204K) Filed: Jun 22, 2026 | ID: 000676

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07436637 Guardant Shield Colorectal Cancer Screening Na Colorectal Cancer Not_Yet_Recruiting 2026-06-30 2027-04-01 ClinicalTrials.gov
NCT07620535 Decision Counseling and Follow-up for Shield+ Patients Colo-rectal Cancer Not_Yet_Recruiting 2026-06-01 2028-06-01 ClinicalTrials.gov
NCT07004413 Continuous or Intermittent Cetuximab Plus FOLFIRI as First-line Treatment in RA… Phase3 Colorectal Cancer Metastatic Not_Yet_Recruiting 2026-01-01 2031-01-01 ClinicalTrials.gov
NCT06880055 Shield Post-Approval Study Protocol Colo-rectal Cancer Recruiting 2025-07-14 2030-12-01 ClinicalTrials.gov
NCT06444542 Understanding Patient Preference on Colorectal Cancer Screening Options-PSU Colo-rectal Cancer Completed 2024-09-16 2025-12-18 ClinicalTrials.gov
NCT05935384 SIBYL: obServation of Therapy Response With lIquid BiopsY evaLuation Non-small Cell Lung Cancer Recruiting 2023-10-25 2030-12-30 ClinicalTrials.gov
NCT06119425 Blood-Based Colorectal Cancer (CRC) Screening Implementation Into Clinical Prac… Na Cancer Colon Completed 2023-10-12 2025-04-30 ClinicalTrials.gov
NCT05703243 Discovering Novel Cancer Treatment Options Using a Comprehensive NGS-based Liqu… Stage III Solid Tumors Unknown 2023-02-01 2025-01-01 ClinicalTrials.gov
NCT05716477 Blood Test (Guardant Shield™) for Screening of Colorectal Cancer in Underserved… Colorectal Carcinoma Completed 2022-12-23 2024-11-30 ClinicalTrials.gov
NCT05117840 Screening for High Frequency Malignant Disease Lung Cancer Active_Not_Recruiting 2022-01-13 2026-12-31 ClinicalTrials.gov
NCT05059444 ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation Bladder Carcinoma Recruiting 2021-09-07 2029-08-01 ClinicalTrials.gov
NCT05641870 Molecular Profiling and Dynamic Changes of ctDNA in Unresectable Locally Advanc… Lung Cancer Unknown 2021-02-01 2023-12-01 ClinicalTrials.gov
NCT04497285 Real World Study Using Comprehensive Genomic Data on the Next Treatment Decisio… Metastatic Breast Cancer Active_Not_Recruiting 2020-10-20 2026-11-30 ClinicalTrials.gov
NCT04436393 Guardant360® Related Clinical Outcomes in Patients Who Share Medical Records-Br… Advanced Breast Cancer Completed 2020-07-02 2022-03-17 ClinicalTrials.gov
NCT04136002 Evaluation of the ctDNA LUNAR Test in an Average Patient Screening Episode Colorectal Cancer Active_Not_Recruiting 2019-10-08 2027-08-05 ClinicalTrials.gov
NCT04087473 Plasma Molecular Profiling in ALK Inhibitor Resistant NSCLC Non-small Cell Lung Cancer Completed 2019-08-23 2025-12-31 ClinicalTrials.gov
NCT03625557 Guardant360® Test-Related Clinical Outcomes in Patients Who Share Medical Recor… Non-Hematologic Malignancy Completed 2019-04-30 2020-04-16 ClinicalTrials.gov
NCT03477474 Registry of Guardant360® Use and Outcomes In People With Advanced Cancer Non-small Cell Lung Cancer Metastatic Terminated 2018-04-06 2019-09-01 ClinicalTrials.gov
NCT03774758 Biomarkers for Risk Stratification in Lung Cancer Nodule Solitary Pulmonary Recruiting 2017-12-17 2030-12-31 ClinicalTrials.gov
NCT03791034 Cell Free DNA for the Diagnosis and Treatment in Early NSCLC Non-small Cell Lung Cancer Recruiting 2017-08-28 2026-12-31 ClinicalTrials.gov
NCT02967770 Molecularly Tailored Therapy to Standard of Care as Second-Line Therapy in Meta… Phase2 Metastatic Pancreatic Cancer Withdrawn 2016-11-01 2018-08-30 ClinicalTrials.gov
NCT03248089 Spanish Lung Liquid vs. Invasive Biopsy Program (SLLIP) Lung Cancer Completed 2016-07-01 2019-01-01 ClinicalTrials.gov
NCT03746262 Changes in Circulating Tumor-Specific DNA in Patients With Non-Metastatic Non-S… Non Small Cell Lung Cancer Completed 2016-05-13 2018-08-10 ClinicalTrials.gov
NCT03615443 Noninvasive vs. Invasive Lung Evaluation Non-Small Cell Lung Cancer Completed 2016-02-12 2020-11-23 ClinicalTrials.gov
Total clinical trials: 24
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Guardant Health ct-DNA LUNAR assay Other Preclinical Nodule Solitary Pulmonary RECRUITING NCT03774758
Decision Counseling Session Other Preclinical Colo-rectal Cancer NOT_YET_RECRUITING NCT07620535
Blood Sample Collection Other Approved Colorectal Cancer NOT_YET_RECRUITING NCT07436637
Screening Reminder Other Approved Colorectal Cancer NOT_YET_RECRUITING NCT07436637
Standard of Care Second Line Therapy Drug Phase PHASE2 Metastatic Pancreatic Cancer WITHDRAWN NCT02967770
Molecularly Tailored Second Line Therapy Drug Phase PHASE2 Metastatic Pancreatic Cancer WITHDRAWN NCT02967770
Guardant360 Other Preclinical Lung Cancer COMPLETED NCT03248089
Guardant360 Other Preclinical Non-Small Cell Lung Cancer COMPLETED NCT03615443
Guardant360 test Other Preclinical Advanced Breast Cancer COMPLETED NCT04436393
Genomic and methylation analysis in liquid biopsy Other Preclinical Lung Cancer UNKNOWN NCT05641870
Chemoradiation treatment regimen and maintenance (if amenable) Drug Preclinical Lung Cancer UNKNOWN NCT05641870
Characterization of the tumoral tissue genomic alterations Other Preclinical Lung Cancer UNKNOWN NCT05641870
Sample collection Other Preclinical Lung Cancer UNKNOWN NCT05641870
EORTC QLQ-30 Other Preclinical Stage III Solid Tumors UNKNOWN NCT05703243
Comprehensive liquid molecular panel test Other Preclinical Stage III Solid Tumors UNKNOWN NCT05703243
Survey Administration Other Preclinical Colorectal Carcinoma COMPLETED NCT05716477
Biospecimen Collection Other Preclinical Colorectal Carcinoma COMPLETED NCT05716477
Guardant Health ct-DNA LUNAR assay Other Preclinical Nodule Solitary Pulmonary RECRUITING NCT03774758
Guardant360 ctDNA assay Other Phase PHASE3 Colorectal Cancer Metastatic NOT_YET_RECRUITING NCT07004413
FOLFIRI+cetuximab Other Phase PHASE3 Colorectal Cancer Metastatic NOT_YET_RECRUITING NCT07004413
blood sample collection and collection of tumor tissue block Other Preclinical Metastatic Breast Cancer ACTIVE_NOT_RECRUITING NCT04497285
Guardant360 Other Preclinical Non-small Cell Lung Cancer RECRUITING NCT05935384
Guardant Reveal Other Preclinical Bladder Carcinoma RECRUITING NCT05059444
Pemetrexed Other Phase PHASE2 Metastatic Non-small Cell Lung Cancer RECRUITING NCT04410796
Carboplatin Other Phase PHASE2 Metastatic Non-small Cell Lung Cancer RECRUITING NCT04410796
Osimertinib Other Phase PHASE2 Metastatic Non-small Cell Lung Cancer RECRUITING NCT04410796
blood-based CRC screening Other Approved Cancer Colon COMPLETED NCT06119425
Guardant Shield Other Preclinical Colo-rectal Cancer COMPLETED NCT06444542
Shield Blood Test for colo-rectal cancer Screening Other Preclinical Colo-rectal Cancer RECRUITING NCT06880055
Low-dose CT scan Other Preclinical Lung Cancer ACTIVE_NOT_RECRUITING NCT05117840
Low-dose CT scan Other Preclinical Lung Cancer ACTIVE_NOT_RECRUITING NCT05117840
Low-dose CT scan Other Preclinical Lung Cancer ACTIVE_NOT_RECRUITING NCT05117840
Low-dose CT scan Other Preclinical Lung Cancer ACTIVE_NOT_RECRUITING NCT05117840
Low-dose CT scan Other Preclinical Lung Cancer ACTIVE_NOT_RECRUITING NCT05117840
Low-dose CT scan Other Preclinical Lung Cancer ACTIVE_NOT_RECRUITING NCT05117840
Low-dose CT scan Other Preclinical Lung Cancer ACTIVE_NOT_RECRUITING NCT05117840
Blood Sample Collection PROCEDURE Approved Colorectal Cancer NOT_YET_RECRUITING NCT07436637
Screening Reminder BEHAVIORAL Approved Colorectal Cancer NOT_YET_RECRUITING NCT07436637
FOLFIRI+cetuximab DRUG Phase PHASE3 Colorectal Cancer Metastatic NOT_YET_RECRUITING NCT07004413
Guardant Shield BEHAVIORAL Preclinical Colo-rectal Cancer COMPLETED NCT06444542
Survey Administration OTHER Preclinical Colorectal Carcinoma COMPLETED NCT05716477
Biospecimen Collection PROCEDURE Preclinical Colorectal Carcinoma COMPLETED NCT05716477
EORTC QLQ-30 OTHER Preclinical Stage III Solid Tumors UNKNOWN NCT05703243
Chemoradiation treatment regimen and maintenance (if amenable) DRUG Preclinical Lung Cancer UNKNOWN NCT05641870
Sample collection PROCEDURE Preclinical Lung Cancer UNKNOWN NCT05641870
Low-dose CT scan DEVICE Preclinical Lung Cancer ACTIVE_NOT_RECRUITING NCT05117840
blood sample collection and collection of tumor tissue block OTHER Preclinical Metastatic Breast Cancer ACTIVE_NOT_RECRUITING NCT04497285
Pemetrexed DRUG Phase PHASE2 Metastatic Non-small Cell Lung Cancer RECRUITING NCT04410796
Carboplatin DRUG Phase PHASE2 Metastatic Non-small Cell Lung Cancer RECRUITING NCT04410796
Osimertinib DRUG Phase PHASE2 Metastatic Non-small Cell Lung Cancer RECRUITING NCT04410796
Standard of Care Second Line Therapy DRUG Phase PHASE2 Metastatic Pancreatic Cancer WITHDRAWN NCT02967770
Molecularly Tailored Second Line Therapy OTHER Phase PHASE2 Metastatic Pancreatic Cancer WITHDRAWN NCT02967770
Total products: 52