SymbolNRIX
NameNURIX THERAPEUTICS, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address1700 OWENS STREET,SUITE 205, SAN FRANCISCO, California, 94158, United States
Telephone+1 415 660-5320
Fax
Email
Websitehttp://www.nurixtx.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001549595
Description

Nurix Therapeutics Inc is a biopharmaceutical company focused on the discovery, development and commercialization of oral, small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. The companys pipeline comprises targeted protein degraders of Brutons tyrosine kinase, or BTK, a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene-B, or CBL-B, an E3 ligase that regulates T cell activation. Its drug candidate from protein degradation portfolio, NX-2127, is an orally available BTK degrader for the treatment of relapsed or refractory B-cell malignancies. Its drug candidate from E3 ligase inhibitor portfolio, NX-1607, is an orally available CBL-B inhibitor for immuno-oncology indications.

Additional info from NASDAQ:
Nurix Therapeutics Inc is a biopharmaceutical company focused on the discovery, development and commercialization of oral, small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. The companys pipeline comprises targeted protein degraders of Brutons tyrosine kinase, or BTK, a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene-B, or CBL-B, an E3 ligase that regulates T cell activation. Its drug candidate from protein degradation portfolio, NX-2127, is an orally available BTK degrader for the treatment of relapsed or refractory B-cell malignancies. Its drug candidate from E3 ligase inhibitor portfolio, NX-1607, is an orally available CBL-B inhibitor for immuno-oncology indications.

2026-07-02 22:02

Ring Christine 🟡 adjusted position in 11.0K shares (2 derivative) of Nurix Therapeutics, Inc. (NRIX) at $23.56 Transaction Date: Jul 02, 2026 | Filing ID: 000024

Read more
2026-07-02 20:28

📋 CHRISTINE RING (Officer) plans to sell 11K shares of NURIX THERAPEUTICS, INC. (at $23.91 each, total $263K) Filed: Jul 02, 2026 | ID: 006819

Read more
2026-06-25 22:49

Hansen Gwenn 🔴 sold 5.4K shares of Nurix Therapeutics, Inc. (NRIX) at $20.00 Transaction Date: Jun 25, 2026 | Filing ID: 000010

Read more
2026-06-25 22:38

Ring Christine 🟡 adjusted position in 28.9K shares (2 derivative) of Nurix Therapeutics, Inc. (NRIX) at $20.06 ($1.0M) Transaction Date: Jun 25, 2026 | Filing ID: 000022

Read more
2026-06-25 20:24

📋 CHRISTINE RING (Officer) plans to sell 29K shares of NURIX THERAPEUTICS INC (at $19.30 each, total $558K) Filed: Jun 25, 2026 | ID: 006501

Read more
2026-06-25 20:24

📋 GWENN M HANSEN (Officer) plans to sell 5K shares of NURIX THERAPEUTICS INC (at $19.30 each, total $104K) Filed: Jun 25, 2026 | ID: 006499

Read more
2026-06-11 11:06

(90% Positive) NURIX THERAPEUTICS, INC. (NRIX) Provides Update on Results for BTK Degrader Bexobrutideg

Read more
2026-06-11 11:00

Nurix Therapeutics to Report Updated Phase 1a/b Results for BTK Degrader Bexobrutideg, Highlighting Durable Responses in Relapsed/Refractory CLL/SLL and Promising Activity in Earlier Lines of Therapy

Read more
2026-06-08 10:11

(19% Negative) NURIX THERAPEUTICS, INC. (NRIX) Announces Delay in milestones Trials for potential total payments of up to $2 Due to Patient Enrollment Issues, Regulatory Process, Safety Review, Efficacy Assessment

Read more
2026-06-08 05:00

Nurix Therapeutics Announces Global Collaboration with Roche to Co-Develop and Co-Commercialize Potential Best-in-Class BTK Degrader Bexobrutideg Across Malignant Hematology, Immunology and Neurology

Read more
Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07516093 Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL Phase3 B-cell Lymphoma Not_Yet_Recruiting 2026-06-01 2032-06-01 ClinicalTrials.gov
NCT07520006 Study of NX-5948 in Combination With Other Agents in Adults With B-cell Maligna… Phase1 B-cell Lymphoma Not_Yet_Recruiting 2026-05-01 2033-05-01 ClinicalTrials.gov
NCT07221500 A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Ty… Phase2 Chronic Lymphocytic Leukemia (CLL) Recruiting 2025-10-15 2030-10-01 ClinicalTrials.gov
NCT06717269 Relative Bioavailability of NX-5948 Tablets vs Capsules and the Effect of Covar… Phase1 Healthy Volunteer Recruiting 2024-11-30 2026-08-01 ClinicalTrials.gov
NCT06691828 Absolute Bioavailability, Absorption, Metabolism, Excretion, and Mass Balance S… Phase1 Healthy Volunteer Completed 2024-11-01 2024-12-05 ClinicalTrials.gov
NCT06593457 A Food-Effect, Drug-Drug Interaction, and Pharmacokinetics Study of NX-5948 in … Phase1 Healthy Volunteers Completed 2024-08-20 2024-11-14 ClinicalTrials.gov
NCT05131022 A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies Phase1 Chronic Lymphocytic Leukemia (CLL) Recruiting 2022-04-13 2028-01-01 ClinicalTrials.gov
NCT05107739 A Study of DeTIL-0255 in Adults With Advanced Malignancies Phase1 Platinum-resistant Ovarian Cancer Terminated 2021-12-22 2023-05-09 ClinicalTrials.gov
NCT05107674 A Study of NX-1607 in Adults With Advanced Malignancies Phase1 Ovarian Cancer, Epithelial Recruiting 2021-09-29 2028-02-28 ClinicalTrials.gov
NCT04830137 A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies Phase1 Chronic Lymphocytic Leukemia (CLL) Recruiting 2021-05-05 2027-05-01 ClinicalTrials.gov
Total clinical trials: 10
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
NX-5948 Other Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT05131022
NX-5948 Other Phase PHASE2 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT07221500
NX-5948 Other Phase PHASE2 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT07221500
NX-5948 Other Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT05131022
NX-5948 Other Phase PHASE2 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT07221500
Drug Product De-TIL-0255 Drug Phase PHASE1 Platinum-resistant Ovarian Cancer TERMINATED NCT05107739
NX-5948 Other Phase PHASE1 Healthy Volunteer COMPLETED NCT06691828
Matching Placebo Other Phase PHASE1 Healthy Volunteers COMPLETED NCT06593457
Paclitaxel Other Phase PHASE1 Ovarian Cancer, Epithelial RECRUITING NCT05107674
NX-1607 Other Phase PHASE1 Ovarian Cancer, Epithelial RECRUITING NCT05107674
Esomeprazole Other Phase PHASE1 Healthy Volunteer RECRUITING NCT06717269
NX-5948 Other Phase PHASE1 Healthy Volunteer RECRUITING NCT06717269
NX-2127 Other Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT04830137
NX-5948 Other Phase PHASE2 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT07221500
NX-5948 Other Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT05131022
Pirtobrutinib DRUG Phase PHASE3 B-cell Lymphoma NOT_YET_RECRUITING NCT07516093
Esomeprazole DRUG Phase PHASE1 Healthy Volunteer RECRUITING NCT06717269
Matching Placebo DRUG Phase PHASE1 Healthy Volunteers COMPLETED NCT06593457
IP DRUG Phase PHASE1 Healthy Volunteers COMPLETED NCT06593457
NX-5948 DRUG Phase PHASE3 B-cell Lymphoma NOT_YET_RECRUITING NCT07516093
Drug Product De-TIL-0255 BIOLOGICAL Phase PHASE1 Platinum-resistant Ovarian Cancer TERMINATED NCT05107739
Paclitaxel DRUG Phase PHASE1 Ovarian Cancer, Epithelial RECRUITING NCT05107674
NX-1607 DRUG Phase PHASE1 Ovarian Cancer, Epithelial RECRUITING NCT05107674
NX-2127 DRUG Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT04830137
Total products: 24