SymbolNRIX
NameNURIX THERAPEUTICS, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address1700 OWENS STREET,SUITE 205, SAN FRANCISCO, California, 94158, United States
Telephone+1 415 660-5320
Fax
Email
Websitehttp://www.nurixtx.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001549595
Description

Nurix Therapeutics Inc is a biopharmaceutical company focused on the discovery, development and commercialization of oral, small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. The companys pipeline comprises targeted protein degraders of Brutons tyrosine kinase, or BTK, a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene-B, or CBL-B, an E3 ligase that regulates T cell activation. Its drug candidate from protein degradation portfolio, NX-2127, is an orally available BTK degrader for the treatment of relapsed or refractory B-cell malignancies. Its drug candidate from E3 ligase inhibitor portfolio, NX-1607, is an orally available CBL-B inhibitor for immuno-oncology indications.

Additional info from NASDAQ:
Nurix Therapeutics Inc is a biopharmaceutical company focused on the discovery, development and commercialization of oral, small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. The companys pipeline comprises targeted protein degraders of Brutons tyrosine kinase, or BTK, a B-cell signaling protein, and inhibitors of Casitas B-lineage lymphoma proto-oncogene-B, or CBL-B, an E3 ligase that regulates T cell activation. Its drug candidate from protein degradation portfolio, NX-2127, is an orally available BTK degrader for the treatment of relapsed or refractory B-cell malignancies. Its drug candidate from E3 ligase inhibitor portfolio, NX-1607, is an orally available CBL-B inhibitor for immuno-oncology indications.

2026-08-14 17:25

New Form SCHEDULE 13G/A - Nurix Therapeutics, Inc. <b>Filed:</b> 2026-08-14 <b>AccNo:</b> 0001104659-26-097194 <b>Size:</b> 13 KB

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2026-08-14 09:37

New Form SCHEDULE 13G/A - Nurix Therapeutics, Inc. <b>Filed:</b> 2026-08-14 <b>AccNo:</b> 0001172661-26-003488 <b>Size:</b> 11 KB

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2026-08-04 05:00

Nurix Therapeutics Announces First Patient Enrolled in Registrational Phase 3 DAYBreak CLL-306 Trial of Bexobrutideg in Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

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2026-08-03 21:51

Ring Christine 🟡 adjusted position in 16.6K shares (1 derivative) of Nurix Therapeutics, Inc. (NRIX) at $23.05 Transaction Date: Aug 03, 2026 | Filing ID: 000028

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2026-07-30 21:58

van Houte Hans 🟡 adjusted position in 2.8K shares (3 derivative) of Nurix Therapeutics, Inc. (NRIX) at $23.38 Transaction Date: Jul 30, 2026 | Filing ID: 000010

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2026-07-30 21:56

Ring Christine 🟡 adjusted position in 3.8K shares (3 derivative) of Nurix Therapeutics, Inc. (NRIX) at $23.38 Transaction Date: Jul 30, 2026 | Filing ID: 000026

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2026-07-30 21:50

Hansen Gwenn 🟡 adjusted position in 3.8K shares (3 derivative) of Nurix Therapeutics, Inc. (NRIX) at $23.38 Transaction Date: Jul 30, 2026 | Filing ID: 000012

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2026-07-21 20:01

Nurix Therapeutics Announces HSR Clearance of Global Collaboration with Roche to Co-Develop and Co-Commercialize Potential Best-in-Class BTK Degrader Bexobrutideg Across Malignant Hematology, Immunology and Neurology

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2026-07-02 22:02

Ring Christine 🟡 adjusted position in 11.0K shares (2 derivative) of Nurix Therapeutics, Inc. (NRIX) at $23.56 Transaction Date: Jul 02, 2026 | Filing ID: 000024

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2026-07-02 20:28

📋 CHRISTINE RING (Officer) plans to sell 11K shares of NURIX THERAPEUTICS, INC. (at $23.91 each, total $263K) Filed: Jul 02, 2026 | ID: 006819

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07516093 Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL Phase3 B-cell Lymphoma Not_Yet_Recruiting 2026-06-01 2032-06-01 ClinicalTrials.gov
NCT07520006 Study of NX-5948 in Combination With Other Agents in Adults With B-cell Maligna… Phase1 B-cell Lymphoma Not_Yet_Recruiting 2026-05-01 2033-05-01 ClinicalTrials.gov
NCT07221500 A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Ty… Phase2 Chronic Lymphocytic Leukemia (CLL) Recruiting 2025-10-15 2030-10-01 ClinicalTrials.gov
NCT06717269 A Single and Multiple Ascending Doses, Relative Bioavailability, Food Effect, a… Phase1 Healthy Volunteer Completed 2024-11-30 2026-05-01 ClinicalTrials.gov
NCT06691828 Absolute Bioavailability, Absorption, Metabolism, Excretion, and Mass Balance S… Phase1 Healthy Volunteer Completed 2024-11-01 2024-12-05 ClinicalTrials.gov
NCT06593457 A Food-Effect, Drug-Drug Interaction, and Pharmacokinetics Study of NX-5948 in … Phase1 Healthy Volunteers Completed 2024-08-20 2024-11-14 ClinicalTrials.gov
NCT05131022 A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies Phase1 Chronic Lymphocytic Leukemia (CLL) Recruiting 2022-04-13 2028-01-01 ClinicalTrials.gov
NCT05107739 A Study of DeTIL-0255 in Adults With Advanced Malignancies Phase1 Platinum-resistant Ovarian Cancer Terminated 2021-12-22 2023-05-09 ClinicalTrials.gov
NCT05107674 A Study of NX-1607 in Adults With Advanced Malignancies Phase1 Ovarian Cancer, Epithelial Recruiting 2021-09-29 2028-02-28 ClinicalTrials.gov
NCT04830137 A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies Phase1 Chronic Lymphocytic Leukemia (CLL) Recruiting 2021-05-05 2027-05-01 ClinicalTrials.gov
Total clinical trials: 10
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
NX-5948 Other Phase PHASE2 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT07221500
NX-5948 Other Phase PHASE2 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT07221500
NX-5948 Other Phase PHASE2 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT07221500
Quinidine Other Phase PHASE1 Healthy Volunteer COMPLETED NCT06717269
Rosuvastatin Other Phase PHASE1 Healthy Volunteer COMPLETED NCT06717269
Digoxin Other Phase PHASE1 Healthy Volunteer COMPLETED NCT06717269
Midazolam Other Phase PHASE1 Healthy Volunteer COMPLETED NCT06717269
Famotidine Other Phase PHASE1 Healthy Volunteer COMPLETED NCT06717269
Placebo Other Phase PHASE1 Healthy Volunteer COMPLETED NCT06717269
Esomeprazole Other Phase PHASE1 Healthy Volunteer COMPLETED NCT06717269
NX-5948 Other Phase PHASE1 Healthy Volunteer COMPLETED NCT06717269
NX-5948 Other Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT05131022
NX-5948 Other Phase PHASE2 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT07221500
NX-5948 Other Phase PHASE2 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT07221500
NX-5948 Other Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT05131022
NX-5948 Other Phase PHASE2 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT07221500
Drug Product De-TIL-0255 Drug Phase PHASE1 Platinum-resistant Ovarian Cancer TERMINATED NCT05107739
NX-5948 Other Phase PHASE1 Healthy Volunteer COMPLETED NCT06691828
Matching Placebo Other Phase PHASE1 Healthy Volunteers COMPLETED NCT06593457
Paclitaxel Other Phase PHASE1 Ovarian Cancer, Epithelial RECRUITING NCT05107674
NX-1607 Other Phase PHASE1 Ovarian Cancer, Epithelial RECRUITING NCT05107674
Esomeprazole Other Phase PHASE1 Healthy Volunteer RECRUITING NCT06717269
NX-5948 Other Phase PHASE1 Healthy Volunteer RECRUITING NCT06717269
NX-2127 Other Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT04830137
NX-5948 Other Phase PHASE2 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT07221500
NX-5948 Other Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT05131022
Pirtobrutinib DRUG Phase PHASE3 B-cell Lymphoma NOT_YET_RECRUITING NCT07516093
Esomeprazole DRUG Phase PHASE1 Healthy Volunteer RECRUITING NCT06717269
Matching Placebo DRUG Phase PHASE1 Healthy Volunteers COMPLETED NCT06593457
IP DRUG Phase PHASE1 Healthy Volunteers COMPLETED NCT06593457
NX-5948 DRUG Phase PHASE3 B-cell Lymphoma NOT_YET_RECRUITING NCT07516093
Drug Product De-TIL-0255 BIOLOGICAL Phase PHASE1 Platinum-resistant Ovarian Cancer TERMINATED NCT05107739
Paclitaxel DRUG Phase PHASE1 Ovarian Cancer, Epithelial RECRUITING NCT05107674
NX-1607 DRUG Phase PHASE1 Ovarian Cancer, Epithelial RECRUITING NCT05107674
NX-2127 DRUG Phase PHASE1 Chronic Lymphocytic Leukemia (CLL) RECRUITING NCT04830137
Total products: 35