SymbolQTTB
NameQ32 BIO INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address830 WINTER STREET, WALTHAM, Massachusetts, 02451, United States
Telephone+1 781 999-0232
Fax
Email
Websitehttps://www.q32bio.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001661998
Description

Q32 Bio Inc. is a clinical-stage biotechnology company. The Company is engaged in developing biologic therapeutics targeting potent regulators of the innate and adaptive immune systems to re-balance immunity in autoimmune and inflammatory diseases. Its lead programs, focused on the IL-7 / TSLP receptor pathways and complement system, address immune dysregulation to help patients take back control of their lives. Its program for adaptive immunity, bempikibart (ADX-914), is a fully human anti-IL-7Ra antibody that re-regulates adaptive immune function for the treatment of autoimmune diseases. It is being evaluated in two Phase II trials for the treatment of atopic dermatitis and alopecia areata. Its program for innate immunity, ADX-097, is based on a platform enabling tissue-targeted regulation of the complement system without long-term systemic blockade. The Company has completed a first-in-human, Phase I ascending dose clinical study of ADX-097 in healthy volunteers.

Additional info from NASDAQ:
Q32 Bio Inc. is a clinical-stage biotechnology company. The Company is engaged in developing biologic therapeutics targeting potent regulators of the innate and adaptive immune systems to re-balance immunity in autoimmune and inflammatory diseases. Its lead programs, focused on the IL-7 / TSLP receptor pathways and complement system, address immune dysregulation to help patients take back control of their lives. Its program for adaptive immunity, bempikibart (ADX-914), is a fully human anti-IL-7Ra antibody that re-regulates adaptive immune function for the treatment of autoimmune diseases. It is being evaluated in two Phase II trials for the treatment of atopic dermatitis and alopecia areata. Its program for innate immunity, ADX-097, is based on a platform enabling tissue-targeted regulation of the complement system without long-term systemic blockade. The Company has completed a first-in-human, Phase I ascending dose clinical study of ADX-097 in healthy volunteers.

2026-07-06 20:20

New Form SCHEDULE 13G/A - Q32 Bio Inc. <b>Filed:</b> 2026-07-06 <b>AccNo:</b> 0001493152-26-032227 <b>Size:</b> 20 KB

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2026-06-25 17:12

New Form S-3 - Q32 Bio Inc. <b>Filed:</b> 2026-06-25 <b>AccNo:</b> 0001193125-26-282783 <b>Size:</b> 1 MB

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2026-06-16 20:30

LAPORTE KATHLEEN 🟢 acquired 9.8K shares (1 derivative) of Q32 Bio Inc. (QTTB) at $12.64 Transaction Date: Jun 12, 2026 | Filing ID: 272701

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2026-06-16 20:30

Iwicki Mark T 🟢 acquired 9.8K shares (1 derivative) of Q32 Bio Inc. (QTTB) at $12.64 Transaction Date: Jun 12, 2026 | Filing ID: 272700

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2026-06-16 20:30

Manke Isaac 🟢 acquired 9.8K shares (1 derivative) of Q32 Bio Inc. (QTTB) at $12.64 Transaction Date: Jun 12, 2026 | Filing ID: 272698

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2026-06-16 20:30

TZIANABOS ARTHUR 🟢 acquired 9.8K shares (1 derivative) of Q32 Bio Inc. (QTTB) at $12.64 Transaction Date: Jun 12, 2026 | Filing ID: 272697

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2026-06-16 20:30

GRAYZEL DAVID S. 🟢 acquired 9.8K shares (1 derivative) of Q32 Bio Inc. (QTTB) at $12.64 Transaction Date: Jun 12, 2026 | Filing ID: 272692

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2026-06-16 20:30

Thistle Mary 🟢 acquired 9.8K shares (1 derivative) of Q32 Bio Inc. (QTTB) at $12.64 Transaction Date: Jun 12, 2026 | Filing ID: 272690

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2026-06-16 20:30

Xu Diyong 🟢 acquired 9.8K shares (1 derivative) of Q32 Bio Inc. (QTTB) at $12.64 Transaction Date: Jun 12, 2026 | Filing ID: 272686

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2026-06-16 20:30

Lundberg Sven Ante 🟢 acquired 9.8K shares (1 derivative) of Q32 Bio Inc. (QTTB) at $12.64 Transaction Date: Jun 12, 2026 | Filing ID: 272684

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT06018428 A Phase 2a Proof-of-Concept Trial of Bempikibart (ADX-914) for the Treatment of… Phase2 Alopecia Areata Active_Not_Recruiting 2023-09-12 2026-09-01 ClinicalTrials.gov
NCT05509023 Evaluating Safety and Efficacy of ADX-914 in Patients With Moderate to Severe A… Phase2 Atopic Dermatitis Active_Not_Recruiting 2022-09-30 2024-12-01 ClinicalTrials.gov
NCT04485481 Single and Multiple Ascending Dose Study of ADX-914 in Healthy Adult Volunteers Phase1 Safety Issues Completed 2020-09-08 2022-01-12 ClinicalTrials.gov
Total clinical trials: 3
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
bempikibart (ADX-914) Other Phase PHASE2 Alopecia Areata ACTIVE_NOT_RECRUITING NCT06018428
bempikibart (ADX-914) Other Phase PHASE2 Alopecia Areata ACTIVE_NOT_RECRUITING NCT06018428
bempikibart (ADX-914) Other Phase PHASE2 Alopecia Areata ACTIVE_NOT_RECRUITING NCT06018428
bempikibart (ADX-914) Other Phase PHASE2 Alopecia Areata ACTIVE_NOT_RECRUITING NCT06018428
bempikibart (ADX-914) Other Phase PHASE2 Alopecia Areata ACTIVE_NOT_RECRUITING NCT06018428
Placebo Other Phase PHASE1 Safety Issues COMPLETED NCT04485481
ADX-914 Other Phase PHASE1 Safety Issues COMPLETED NCT04485481
Placebo Other Phase PHASE2 Atopic Dermatitis ACTIVE_NOT_RECRUITING NCT05509023
ADX-914 Other Phase PHASE2 Atopic Dermatitis ACTIVE_NOT_RECRUITING NCT05509023
ADX-097 Other Phase PHASE2 IgA Nephropathy WITHDRAWN NCT06419205
bempikibart (ADX-914) Other Phase PHASE2 Alopecia Areata ACTIVE_NOT_RECRUITING NCT06018428
ADX-097 DRUG Phase PHASE2 IgA Nephropathy WITHDRAWN NCT06419205
bempikibart (ADX-914) DRUG Phase PHASE2 Alopecia Areata ACTIVE_NOT_RECRUITING NCT06018428
Placebo DRUG Phase PHASE2 Atopic Dermatitis ACTIVE_NOT_RECRUITING NCT05509023
ADX-914 DRUG Phase PHASE2 Atopic Dermatitis ACTIVE_NOT_RECRUITING NCT05509023
Total products: 15