SymbolQURE
NameUNIQURE N.V.
SectorHEALTH CARE
RegionEurope
IndustryBiotechnology: Pharmaceutical Preparations
AddressPAASHEUVELWEG 25A, AMSTERDAM, 1105 BP, Netherlands
Telephone+31 20 - 240-6000
Fax
Email
Websitehttps://www.uniqure.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001590560
Description

uniQure NV is a gene therapy company. It develops treatment and platforms for patients suffering from genetic and other devastating diseases. Its products and services are focused on hemophilia, Huntingtons disease, and cardiovascular diseases. The company is focused on the development of the pipeline of gene therapies with the collaboration of Bristol Myers Squibb for cardiovascular diseases.

Additional info from NASDAQ:
uniQure NV is a gene therapy company. It develops treatment and platforms for patients suffering from genetic and other devastating diseases. Its products and services are focused on hemophilia, Huntingtons disease, and cardiovascular diseases. The company is focused on the development of the pipeline of gene therapies with the collaboration of Bristol Myers Squibb for cardiovascular diseases.

2026-07-07 20:47

Director Kapusta Matthew C 🟡 adjusted position in 21.1K shares (1 derivative) of uniQure N.V. (QURE) at $45.89 ($1.8M) Transaction Date: Jul 02, 2026 | Filing ID: 000397

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2026-07-02 20:59

Abi-Saab Walid 🟡 adjusted position in 30.0K shares (1 derivative) of uniQure N.V. (QURE) at $46.46 ($1.5M) Transaction Date: Jun 30, 2026 | Filing ID: 000394

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2026-07-02 20:54

Director Kaye Jack 🟡 adjusted position in 21.2K shares (2 derivative) of uniQure N.V. (QURE) at $46.49 ($2.0M) Transaction Date: Jun 30, 2026 | Filing ID: 000392

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2026-07-02 20:00

📋 Kapusta Matthew C (Officer) plans to sell 21K shares of uniQure N.V. (at $45.15 each, total $952K) Filed: Jul 02, 2026 | ID: 000264

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2026-06-30 21:06

Abi-Saab Walid 🔴 sold 1.4K shares of uniQure N.V. (QURE) at $46.86 Transaction Date: Jun 26, 2026 | Filing ID: 000387

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2026-06-26 21:15

Director Kapusta Matthew C 🟡 adjusted position in 35.4K shares (2 derivative) of uniQure N.V. (QURE) at $50.02 ($3.9M) Transaction Date: Jun 24, 2026 | Filing ID: 000375

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2026-06-25 20:10

uniQure Announces Closing of Upsized Public Offering and Full Exercise by Underwriters of Option to Purchase Additional Shares

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2026-06-25 20:00

📋 Kapusta Matthew C (Officer) plans to sell 29K shares of uniQure N.V. (at $50.02 each, total $1.4M) Filed: Jun 25, 2026 | ID: 000254

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2026-06-24 20:54

(99% Neutral) UNIQURE N.V. (QURE) Announces Clinical Development Update

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2026-06-24 20:01

📋 Kapusta Matthew C (Officer) plans to sell 7K shares of uniQure N.V. (at $50.00 each, total $335K) Filed: Jun 24, 2026 | ID: 000252

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT06100276 Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administe… Phase1 Amyotrophic Lateral Sclerosis Active_Not_Recruiting 2024-08-01 2031-06-30 ClinicalTrials.gov
NCT06063850 AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal… Phase1 Mesial Temporal Lobe Epilepsy Recruiting 2024-06-12 2031-12-01 ClinicalTrials.gov
NCT06270316 Safety, PK/PD, and Exploratory Efficacy Study of AMT-191 in Classic Fabry Disea… Phase1 Fabry Disease Recruiting 2024-06-05 2031-04-30 ClinicalTrials.gov
NCT05243017 Safety and Efficacy of AMT-130 in European Adults With Early Manifest Huntingto… Phase1 Huntington Disease Active_Not_Recruiting 2021-10-07 2029-10-07 ClinicalTrials.gov
NCT04723680 An Exploration of the Impact of Gene Therapy on the Lives of People With Haemop… Hemophilia Completed 2020-08-13 2023-02-28 ClinicalTrials.gov
NCT04120493 Safety and Proof-of-Concept (POC) Study With AMT-130 in Adults With Early Manif… Phase1 Huntington's Disease Active_Not_Recruiting 2019-09-06 2029-12-01 ClinicalTrials.gov
NCT02904772 Alipogene Tiparvovec for the Treatment of LPLD Patients Phase2 LPL Deficiency Withdrawn 2016-10-01 2020-09-01 ClinicalTrials.gov
NCT03293810 Glybera Registry, Lipoprotein Lipase Deficient (LPLD) Patients Lipoprotein Lipase Deficiency Completed 2014-06-27 2023-06-01 ClinicalTrials.gov
NCT03300453 Intracerebral Gene Therapy in Children With Sanfilippo Type B Syndrome Phase1 Sanfilippo Syndrome B Completed 2013-09-17 2019-11-27 ClinicalTrials.gov
NCT02082860 Phase I Gene Therapy Clinical Trial Using the Vector rAAV2/5-PBGD for the Treat… Phase1 Acute Intermittent Porphyria Completed 2012-11-01 2014-11-01 ClinicalTrials.gov
NCT02076763 Observational Study of Acute Intermittent Porphyria Patients Acute Intermittent Porphyria Completed 2011-08-01 2014-02-01 ClinicalTrials.gov
Total clinical trials: 11
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
AAV9-hSyn1-miGRIK2 Other Phase PHASE1 Mesial Temporal Lobe Epilepsy RECRUITING NCT06063850
rAAV2/5-PBGD vector dosage 4 Other Phase PHASE1 Acute Intermittent Porphyria COMPLETED NCT02082860
rAAV2/5-PBGD vector dosage 3 Other Phase PHASE1 Acute Intermittent Porphyria COMPLETED NCT02082860
rAAV2/5-PBGD vector dosage 2 Other Phase PHASE1 Acute Intermittent Porphyria COMPLETED NCT02082860
rAAV2/5-PBGD vector dosage 1 Other Phase PHASE1 Acute Intermittent Porphyria COMPLETED NCT02082860
Mycophenolate mofetil Other Phase PHASE2 LPL Deficiency WITHDRAWN NCT02904772
Cyclosporins Other Phase PHASE2 LPL Deficiency WITHDRAWN NCT02904772
Prednisolone Other Phase PHASE2 LPL Deficiency WITHDRAWN NCT02904772
alipogene tiparvovec Other Phase PHASE2 LPL Deficiency WITHDRAWN NCT02904772
rAAV2/5-hNAGLU Other Phase PHASE1 Sanfilippo Syndrome B COMPLETED NCT03300453
Qualitative interview Other Preclinical Hemophilia COMPLETED NCT04723680
Qualitative interview Other Preclinical Hemophilia COMPLETED NCT04723680
Observational study Other Preclinical Lipoprotein Lipase Deficiency COMPLETED NCT03293810
Observational study Other Preclinical Lipoprotein Lipase Deficiency COMPLETED NCT03293810
intra-striatal rAAV5-miHTT Other Phase PHASE1 Huntington Disease ACTIVE_NOT_RECRUITING NCT05243017
intra-striatal rAAV5-miHTT Other Phase PHASE1 Huntington Disease ACTIVE_NOT_RECRUITING NCT05243017
AAV9-hSyn1-miGRIK2 Other Phase PHASE1 Mesial Temporal Lobe Epilepsy RECRUITING NCT06063850
AAV9-hSyn1-miGRIK2 Other Phase PHASE1 Mesial Temporal Lobe Epilepsy RECRUITING NCT06063850
Imitation (sham) surgery Procedure Phase PHASE1 Huntington's Disease ACTIVE_NOT_RECRUITING NCT04120493
intra-striatal rAAV5-miHTT Other Phase PHASE1 Huntington's Disease ACTIVE_NOT_RECRUITING NCT04120493
Imitation (sham) surgery Procedure Phase PHASE1 Huntington's Disease ACTIVE_NOT_RECRUITING NCT04120493
intra-striatal rAAV5-miHTT Other Phase PHASE1 Huntington's Disease ACTIVE_NOT_RECRUITING NCT04120493
AMT-162 Other Phase PHASE1 Amyotrophic Lateral Sclerosis ACTIVE_NOT_RECRUITING NCT06100276
AMT-162 Other Phase PHASE1 Amyotrophic Lateral Sclerosis ACTIVE_NOT_RECRUITING NCT06100276
AMT-191 Other Phase PHASE1 Fabry Disease RECRUITING NCT06270316
AMT-191 Other Phase PHASE1 Fabry Disease RECRUITING NCT06270316
rAAV2/5-hNAGLU DRUG Phase PHASE1 Sanfilippo Syndrome B COMPLETED NCT03300453
Mycophenolate mofetil DRUG Phase PHASE2 LPL Deficiency WITHDRAWN NCT02904772
Cyclosporins DRUG Phase PHASE2 LPL Deficiency WITHDRAWN NCT02904772
Prednisolone DRUG Phase PHASE2 LPL Deficiency WITHDRAWN NCT02904772
alipogene tiparvovec DRUG Phase PHASE2 LPL Deficiency WITHDRAWN NCT02904772
rAAV2/5-PBGD vector dosage 4 GENETIC Phase PHASE1 Acute Intermittent Porphyria COMPLETED NCT02082860
rAAV2/5-PBGD vector dosage 3 GENETIC Phase PHASE1 Acute Intermittent Porphyria COMPLETED NCT02082860
rAAV2/5-PBGD vector dosage 2 GENETIC Phase PHASE1 Acute Intermittent Porphyria COMPLETED NCT02082860
rAAV2/5-PBGD vector dosage 1 GENETIC Phase PHASE1 Acute Intermittent Porphyria COMPLETED NCT02082860
Total products: 35