SymbolRAPP
NameRAPPORT THERAPEUTICS, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
Address1325 BOYLSTON STREET,,SUITE 401, BOSTON, Massachusetts, 02215, United States
Telephone857-321-8020
Fax
Email
Websitehttps://www.rapportrx.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0002012593
Description

Rapport Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of small molecule medicines for patients suffering from central nervous system (CNS) disorders. Its lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. The company also develops RAP-199, a TARPy8 targeted molecule with differentiated chemical and pharmacokinetic properties; and nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and a9a10 nAChR for the treatment of hearing disorders. Rapport Therapeutics, Inc. was incorporated in 2022 and is headquartered in Boston, Massachusetts.

Additional info from NASDAQ:
Rapport Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the discovery and development of small molecule medicines for patients suffering from central nervous system (CNS) disorders. Its lead product candidate is receptor associated protein (RAP)-219, an investigational small molecule that is designed to inhibit TARPy8-containing AMPARs with picomolar affinity for the treatment of focal epilepsy and other CNS disorders, including peripheral neuropathic pain and bipolar disorder. The company also develops RAP-199, a TARPy8 targeted molecule with differentiated chemical and pharmacokinetic properties; and nicotinic acetylcholine receptor (nAChR) programs, such as a6 nAChR to treat chronic pain and a9a10 nAChR for the treatment of hearing disorders. Rapport Therapeutics, Inc. was incorporated in 2022 and is headquartered in Boston, Massachusetts.

2026-06-29 20:45

📋 Abraham N. Ceesay (Officer) plans to sell 99K shares of RAPPORT THERAPEUTICS, INC. (at $40.39 each, total $4.0M) Filed: Jun 29, 2026 | ID: 000411

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2026-06-10 21:57

MARAGANORE JOHN 🟢 acquired 15.2K shares (1 derivative) of Rapport Therapeutics, Inc. (RAPP) at $35.21 Transaction Date: Jun 10, 2026 | Filing ID: 266155

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2026-06-10 21:52

PEREZ ROBERT J 🟢 acquired 15.2K shares (1 derivative) of Rapport Therapeutics, Inc. (RAPP) at $35.21 Transaction Date: Jun 10, 2026 | Filing ID: 266147

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2026-06-10 21:28

Silva Paul M 🟢 acquired 15.2K shares (1 derivative) of Rapport Therapeutics, Inc. (RAPP) at $35.21 Transaction Date: Jun 10, 2026 | Filing ID: 266099

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2026-06-10 21:26

HEALY JAMES 🟢 acquired 15.2K shares (1 derivative) of Rapport Therapeutics, Inc. (RAPP) at $35.21 Transaction Date: Jun 10, 2026 | Filing ID: 266095

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2026-06-10 21:25

Huber Reid M 🟢 acquired 15.2K shares (1 derivative) of Rapport Therapeutics, Inc. (RAPP) at $35.21 Transaction Date: Jun 10, 2026 | Filing ID: 266090

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2026-06-10 21:24

Young Wendy B. 🟢 acquired 15.2K shares (1 derivative) of Rapport Therapeutics, Inc. (RAPP) at $35.21 Transaction Date: Jun 10, 2026 | Filing ID: 266086

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2026-06-10 21:23

Sanchez Ramiro 🟢 acquired 15.2K shares (1 derivative) of Rapport Therapeutics, Inc. (RAPP) at $35.21 Transaction Date: Jun 10, 2026 | Filing ID: 266080

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2026-06-10 20:12

(99% Neutral) RAPPORT THERAPEUTICS, INC. (RAPP) Files Form 8-K

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2026-05-28 20:15

Third Rock Ventures V, L.P. 🔴 sold 18.6K shares of Rapport Therapeutics, Inc. (RAPP) at $40.05 Transaction Date: May 26, 2026 | Filing ID: 245259

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT07563881 Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With … Phase3 Focal Seizure Recruiting 2026-06-05 2029-09-01 ClinicalTrials.gov
NCT07594119 Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With … Phase3 Focal Seizure Recruiting 2026-06-01 2029-09-01 ClinicalTrials.gov
NCT07219407 A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Foc… Phase2 Focal Epilepsy Recruiting 2025-12-15 2028-02-03 ClinicalTrials.gov
NCT07046494 Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With … Phase2 Bipolar 1 Disorder Recruiting 2025-07-25 2026-11-01 ClinicalTrials.gov
NCT06377930 Study Evaluating the Safety and Efficacy of RAP-219 in Adult Participants With … Phase2 Focal Onset Seizures Completed 2024-10-10 2025-09-26 ClinicalTrials.gov
Total clinical trials: 5
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07594119
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07594119
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure RECRUITING NCT07563881
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
Placebo Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE3 Focal Seizure NOT_YET_RECRUITING NCT07563881
RAP-219 Other Phase PHASE2 Focal Epilepsy RECRUITING NCT07219407
RAP-219 Other Phase PHASE2 Focal Onset Seizures COMPLETED NCT06377930
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 Other Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
Placebo OTHER Phase PHASE2 Bipolar 1 Disorder RECRUITING NCT07046494
RAP-219 DRUG Phase PHASE2 Focal Epilepsy RECRUITING NCT07219407
Total products: 180