SymbolTECX
NameTECTONIC THERAPEUTIC, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Biological Products (No Diagnostic Substances)
AddressONE KENDALL SQUARE,BUILDING 300, SUITE 201, CAMBRIDGE, Massachusetts, 02139, United States
Telephone+1 617 914-8420
Fax
Email
Websitehttps://www.tectonictx.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0001681087
Description

Tectonic Therapeutic, Inc. is a biotechnology company. The Company is focused on the discovery and development of therapeutic proteins and antibodies that modulate the activity of G-protein coupled receptors (GPCRs). Leveraging its technology platform called GEODe (GPCRs Engineered for Optimal Discovery), the Company is focused on developing biologic medicines that overcome the existing challenges of GPCR-targeted drug discovery and harness the human body to modify the course of disease. The Companys lead program, TX000045 (TX45), is an Fc-relaxin fusion molecule that activates the RXFP1 receptor, the GPCR target of the hormone relaxin. TX45 is being evaluated in Phase Ia/Ib clinical trials as a potential treatment for Group 2 Pulmonary Hypertension with Heart Failure with Preserved Ejection Fraction (HFpEF). Its second program addresses Hereditary Hemorrhagic Telangiectasia (HHT).

Additional info from NASDAQ:
Tectonic Therapeutic, Inc. is a biotechnology company. The Company is focused on the discovery and development of therapeutic proteins and antibodies that modulate the activity of G-protein coupled receptors (GPCRs). Leveraging its technology platform called GEODe (GPCRs Engineered for Optimal Discovery), the Company is focused on developing biologic medicines that overcome the existing challenges of GPCR-targeted drug discovery and harness the human body to modify the course of disease. The Companys lead program, TX000045 (TX45), is an Fc-relaxin fusion molecule that activates the RXFP1 receptor, the GPCR target of the hormone relaxin. TX45 is being evaluated in Phase Ia/Ib clinical trials as a potential treatment for Group 2 Pulmonary Hypertension with Heart Failure with Preserved Ejection Fraction (HFpEF). Its second program addresses Hereditary Hemorrhagic Telangiectasia (HHT).

2026-06-23 21:52

REICIN ALISE 🔴 sold 924 shares of Tectonic Therapeutic, Inc. (TECX) at $30.34 Transaction Date: Jun 20, 2026 | Filing ID: 000012

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2026-06-12 20:30

Lochner Daniel 🟢 acquired 7.5K shares (1 derivative) of Tectonic Therapeutic, Inc. (TECX) at $16.80 Transaction Date: Jun 11, 2026 | Filing ID: 000006

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2026-06-10 21:08

(85% Positive) TECTONIC THERAPEUTIC, INC. (TECX) Announces Enrollment Update for enrollment Due to Patient Enrollment Issues, Regulatory Process, Manufacturing Considerations, Safety Review, Efficacy Assessment

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2026-06-10 20:45

SPRINGER TIMOTHY A 🟢 acquired 10.2K shares (1 derivative) of Tectonic Therapeutic, Inc. (TECX) at $28.56 Transaction Date: Jun 09, 2026 | Filing ID: 000003

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2026-06-10 20:45

Tipirneni Praveen P. 🟢 acquired 10.2K shares (1 derivative) of Tectonic Therapeutic, Inc. (TECX) at $28.56 Transaction Date: Jun 09, 2026 | Filing ID: 000003

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2026-06-10 20:45

Donenberg Phillip B. 🟢 acquired 10.2K shares (1 derivative) of Tectonic Therapeutic, Inc. (TECX) at $28.56 Transaction Date: Jun 09, 2026 | Filing ID: 000010

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2026-06-10 20:36

Chutter Jessica Caroline 🟢 acquired 20.4K shares (1 derivative) of Tectonic Therapeutic, Inc. (TECX) at $29.10 Transaction Date: Jun 08, 2026 | Filing ID: 000007

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2026-06-10 20:01

Tectonic Therapeutic Completes Enrollment in TX45 APEX Phase 2 Clinical Trial in PH-HFpEF Patients

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2026-06-10 17:35

New Form 3 - Tectonic Therapeutic, Inc. <b>Filed:</b> 2026-06-10 <b>AccNo:</b> 0002123815-26-000006 <b>Size:</b> 8 KB

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2026-05-07 20:23

(30% Negative) TECTONIC THERAPEUTIC, INC. (TECX) Reports Q2 2026 Financial Results

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT06616974 A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart … Phase2 Pulmonary Hypertension Active_Not_Recruiting 2024-09-04 2027-01-05 ClinicalTrials.gov
Total clinical trials: 1
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Placebo Other Phase PHASE2 Pulmonary Hypertension ACTIVE_NOT_RECRUITING NCT06616974
TX000045- Dose B Other Phase PHASE2 Pulmonary Hypertension ACTIVE_NOT_RECRUITING NCT06616974
TX000045- Dose A Other Phase PHASE2 Pulmonary Hypertension ACTIVE_NOT_RECRUITING NCT06616974
Placebo Other Phase PHASE2 Pulmonary Hypertension RECRUITING NCT06616974
TX000045- Dose B Other Phase PHASE2 Pulmonary Hypertension RECRUITING NCT06616974
TX000045- Dose A Other Phase PHASE2 Pulmonary Hypertension RECRUITING NCT06616974
Total products: 6