SymbolTENX
NameTENAX THERAPEUTICS, INC.
SectorHEALTH CARE
RegionNorth America
IndustryBiotechnology: Pharmaceutical Preparations
AddressONE COPLEY PARKWAY,SUITE 490, MORRISVILLE, North Carolina, 27560, United States
Telephone+1 919 855-2100
Fax
Email
Websitehttps://www.tenaxthera.com
IncorporationUNDEFINED
Incorporated On
Employees
Fiscal Year
Public Since
ExchangesNASDAQ
Auditor
Audit StatusNOT PROVIDED
Reporting Status
CIK0000034956
Description

Tenax Therapeutics, Inc., is a specialty pharmaceutical company focused on identifying, developing, and commercializing products that address cardiovascular and pulmonary diseases with high unmet medical need. The Company has a world-class scientific advisory team including recognized global experts in pulmonary hypertension. The Company owns North American rights to develop and commercialize levosimendan and has recently released topline data regarding their Phase 2 clinical trial for the use of levosimendan in the treatment of Pulmonary Hypertension associated with Heart Failure and preserved Ejection Fraction (PH-HFpEF). For more information, visit www.tenaxthera.com.

Additional info from NASDAQ:
Tenax Therapeutics, Inc., is a specialty pharmaceutical company focused on identifying, developing, and commercializing products that address cardiovascular and pulmonary diseases with high unmet medical need. The Company has a world-class scientific advisory team including recognized global experts in pulmonary hypertension. The Company owns North American rights to develop and commercialize levosimendan and has recently released topline data regarding their Phase 2 clinical trial for the use of levosimendan in the treatment of Pulmonary Hypertension associated with Heart Failure and preserved Ejection Fraction (PH-HFpEF). For more information, visit www.tenaxthera.com.

2026-07-17 18:59

New Form SCHEDULE 13G/A - TENAX THERAPEUTICS, INC. <b>Filed:</b> 2026-07-17 <b>AccNo:</b> 0001104659-26-084723 <b>Size:</b> 16 KB

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2026-07-02 20:05

Tenax Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

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2026-07-02 12:00

(10% Negative) TENAX THERAPEUTICS, INC. (TENX) Announces Delay in results Trials for August CHAPEL HILL Due to Geopolitical Situation, Pandemic-Related Challenges, Patient Enrollment Issues, Regulatory Process, Manufacturing Considerations

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2026-07-02 11:00

Tenax Therapeutics Announces Late-Breaking Presentation of LEVEL Clinical Trial Data at ESC Congress 2026

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2026-06-29 20:40

(99% Neutral) TENAX THERAPEUTICS, INC. (TENX) Announces Business Combination

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2026-06-05 12:41

New Form SCHEDULE 13G/A - TENAX THERAPEUTICS, INC. <b>Filed:</b> 2026-06-05 <b>AccNo:</b> 0000080255-26-000435 <b>Size:</b> 8 KB

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2026-06-04 20:10

(99% Neutral) TENAX THERAPEUTICS, INC. (TENX) Files Form 8-K

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2026-05-20 18:05

New Form SCHEDULE 13G - TENAX THERAPEUTICS, INC. <b>Filed:</b> 2026-05-20 <b>AccNo:</b> 0001104659-26-064597 <b>Size:</b> 15 KB

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2026-05-15 19:56

New Form SCHEDULE 13G/A - TENAX THERAPEUTICS, INC. <b>Filed:</b> 2026-05-15 <b>AccNo:</b> 0000935836-26-000286 <b>Size:</b> 21 KB

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2026-05-15 18:26

New Form SCHEDULE 13G/A - TENAX THERAPEUTICS, INC. <b>Filed:</b> 2026-05-15 <b>AccNo:</b> 0000935836-26-000280 <b>Size:</b> 18 KB

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Trial ID Title Phase Indication Status Start Date Completion Date Source
NCT02973620 Levosimendan Compassionate Use in Pediatric Patients With Advanced Decompensate… Heart Decompensation No_Longer_Available ClinicalTrials.gov
NCT07436689 Long-Term Open-Label Extension Study of Oral Levosimendan Phase3 Pulmonary Hypertension Associated With HFpEF Enrolling_By_Invitation 2026-03-13 2029-03-01 ClinicalTrials.gov
NCT07288398 LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2 Phase3 Pulmonary Hypertension Associated With HFpEF Recruiting 2026-03-03 2029-06-30 ClinicalTrials.gov
NCT05983250 LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF Phase3 Pulmonary Hypertension Active_Not_Recruiting 2024-01-10 2028-10-01 ClinicalTrials.gov
NCT03624010 Open-Label Rollover Study of Levosimendan in PH-HFpEF Patients Phase2 Hypertension Pulmonary Secondary Heart Failure Completed 2019-04-09 2023-04-25 ClinicalTrials.gov
NCT03541603 Hemodynamic Evaluation of Levosimendan in Patients With PH-HFpEF Phase2 Hypertension Pulmonary Secondary Completed 2018-11-14 2020-04-07 ClinicalTrials.gov
NCT02025621 Levosimendan in Patients With Left Ventricular Systolic Dysfunction Undergoing … Phase3 Coronary Artery Bypass Grafting Completed 2014-07-01 2016-11-01 ClinicalTrials.gov
NCT00908063 Safety and Tolerability of Oxycyte in Patients With Traumatic Brain Injury (TBI) Phase2 Traumatic Brain Injury Terminated 2009-10-01 2014-09-01 ClinicalTrials.gov
NCT00174980 Study of Oxycyte in Severe Closed Head Injury Phase2 Traumatic Brain Injury Terminated 2005-09-01 2008-04-01 ClinicalTrials.gov
Total clinical trials: 9
Product Name Type Development Stage Therapeutic Area Study Status Trial ID
Placebo Other Phase PHASE3 Pulmonary Hypertension ACTIVE_NOT_RECRUITING NCT05983250
TNX-103 Other Phase PHASE3 Pulmonary Hypertension ACTIVE_NOT_RECRUITING NCT05983250
TNX-103 Other Phase PHASE3 Pulmonary Hypertension Associated With HFpEF ENROLLING_BY_INVITATION NCT07436689
Levosimendan Other Preclinical Heart Decompensation NO_LONGER_AVAILABLE NCT02973620
Placebo Other Phase PHASE3 Coronary Artery Bypass Grafting COMPLETED NCT02025621
Levosimendan Other Phase PHASE3 Coronary Artery Bypass Grafting COMPLETED NCT02025621
Matching Placebo Other Phase PHASE2 Hypertension Pulmonary Secondary COMPLETED NCT03541603
Levosimendan Other Phase PHASE2 Hypertension Pulmonary Secondary COMPLETED NCT03541603
Placebo Other Phase PHASE3 Pulmonary Hypertension RECRUITING NCT05983250
TNX-103 Other Phase PHASE3 Pulmonary Hypertension RECRUITING NCT05983250
Placebo Other Phase PHASE3 Pulmonary Hypertension Associated With HFpEF RECRUITING NCT07288398
TNX-103 Other Phase PHASE3 Pulmonary Hypertension Associated With HFpEF RECRUITING NCT07288398
TNX-103 Other Phase PHASE3 Pulmonary Hypertension Associated With HFpEF ENROLLING_BY_INVITATION NCT07436689
Levosimendan Other Phase PHASE2 Hypertension Pulmonary Secondary Heart Failure COMPLETED NCT03624010
Levosimendan Other Phase PHASE2 Hypertension Pulmonary Secondary Heart Failure COMPLETED NCT03624010
Levosimendan Other Phase PHASE2 Hypertension Pulmonary Secondary Heart Failure COMPLETED NCT03624010
Levosimendan Other Phase PHASE2 Hypertension Pulmonary Secondary Heart Failure COMPLETED NCT03624010
Levosimendan Other Phase PHASE2 Hypertension Pulmonary Secondary Heart Failure COMPLETED NCT03624010
Levosimendan Other Phase PHASE2 Hypertension Pulmonary Secondary Heart Failure COMPLETED NCT03624010
Levosimendan Other Phase PHASE2 Hypertension Pulmonary Secondary Heart Failure COMPLETED NCT03624010
Levosimendan Other Phase PHASE2 Hypertension Pulmonary Secondary Heart Failure COMPLETED NCT03624010
Levosimendan Other Phase PHASE2 Hypertension Pulmonary Secondary Heart Failure COMPLETED NCT03624010
TNX-103 DRUG Phase PHASE3 Pulmonary Hypertension Associated With HFpEF ENROLLING_BY_INVITATION NCT07436689
Levosimendan 2.5 mg/ml Injectable Solution DRUG Phase PHASE2 Hypertension Pulmonary Secondary Heart Failure COMPLETED NCT03624010
Matching Placebo DRUG Phase PHASE2 Hypertension Pulmonary Secondary COMPLETED NCT03541603
Placebo DRUG Phase PHASE3 Pulmonary Hypertension Associated With HFpEF RECRUITING NCT07288398
Levosimendan DRUG Phase PHASE2 Hypertension Pulmonary Secondary COMPLETED NCT03541603
Normal Saline DRUG Phase PHASE2 Traumatic Brain Injury TERMINATED NCT00908063
Oxycyte DRUG Phase PHASE2 Traumatic Brain Injury TERMINATED NCT00908063
Total products: 29