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SUMMIT THERAPEUTICS INC. (SMMT)

(10% Negative) SUMMIT THERAPEUTICS INC. (SMMT) Announces Delay in Progress Trials for clinical studies globally Due to Geopolitical Situation, Pandemic-Related Challenges, Patient Enrollment Issues, Regulatory Process, Safety Review, Efficacy Assessment

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  • News bot April 30, 2026, 8:41 p.m.

    📋 SUMMIT THERAPEUTICS INC. (SMMT) - Clinical Trial Update

    Filing Date: 2026-04-30

    Accepted: 2026-04-30 16:40:49

    Event Type: Clinical Trial Update

    Event Details:

    SUMMIT THERAPEUTICS INC. (SMMT) Announces Clinical Trial Update SUMMIT THERAPEUTICS INC. (SMMT) provided an update on its clinical development programs. Clinical Development Highlights:
    • Drug Program: Progress, Expected
    • Diseases/Conditions: clinical studies globally, China Update Conference Call to be Held on June 1
    • Clinical Stage: Phase III
    • Update Type: Trial Timeline Adjustment
    • Primary Factors: Geopolitical Situation, Pandemic-Related Challenges, Patient Enrollment, Regulatory Process
    • Collaboration: China Update Conference Call
    • Updated Timeline: January 2023
      • Expected in the First Half 2027
      • Expected in Second Half of 2026

    🔬 Clinical Development Pipeline (SUMMIT THERAPEUTICS INC.):

    Product Type Development Stage Therapeutic Area Source
    Change in SARS-CoV-2 Antibody Levels OTHER Preclinical Covid-19 ClinicalTrials.gov
    Ivonescimab Injection Other Phase PHASE3 Non-Small Cell Lung Cancer ClinicalTrials.gov
    Ligufalimab DRUG Phase PHASE3 Squamous Cell Carcinoma Head and Neck Cancer (HNSCC) ClinicalTrials.gov
    Bevacizumab DRUG Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    Drug: Bevacizumab Injection DRUG Phase PHASE3 Metastatic Colorectal Cancer (CRC) ClinicalTrials.gov
    AK112 DRUG Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    Pembrolizumab Injection Other Phase PHASE3 Non-Small Cell Lung Cancer ClinicalTrials.gov
    Ivonescimab 20 mg/kg Other Phase PHASE2 Extensive Stage Lung Small Cell Cancer ClinicalTrials.gov
    Ivonescimab 10 mg/kg Other Phase PHASE2 Extensive Stage Lung Small Cell Cancer ClinicalTrials.gov
    Digital care Other Approved Pregnancy ClinicalTrials.gov
    Standard Care Other Approved Pregnancy ClinicalTrials.gov
    Blister pack Other Approved Pregnancy ClinicalTrials.gov
    Bottle pack Other Approved Pregnancy ClinicalTrials.gov
    Paclitaxel Other Phase PHASE2 Metastatic Esophageal Adenocarcinoma ClinicalTrials.gov
    Irinotecan Other Phase PHASE2 Metastatic Esophageal Adenocarcinoma ClinicalTrials.gov
    FOLFOX regimen Other Phase PHASE2 Metastatic Esophageal Adenocarcinoma ClinicalTrials.gov
    Ivonescimab Other Phase PHASE2 Metastatic Esophageal Adenocarcinoma ClinicalTrials.gov
    Osimertinib Other Phase PHASE1 Non-Small Cell Lung Cancer ClinicalTrials.gov
    Dato-DXd Other Phase PHASE1 Non-Small Cell Lung Cancer ClinicalTrials.gov
    Stereotactic Radiosurgery Procedure Phase PHASE1 Non-Small Cell Lung Cancer ClinicalTrials.gov
    BLOOD PRESSURE MEASUREMENT PROCEDURE Preclinical Peripheral Arterial Disease ClinicalTrials.gov
    BLOOD PRESSURE MEASURMENT PROCEDURE Preclinical Peripheral Arterial Disease ClinicalTrials.gov
    Prescription for Action (SPHERES Model) OTHER Approved Pregnancy ClinicalTrials.gov
    Placebo Acupuncture PROCEDURE Phase PHASE3 Fatigue ClinicalTrials.gov
    Acupuncture PROCEDURE Phase PHASE3 Fatigue ClinicalTrials.gov
    WAYA-Holiday OTHER Approved Cancer ClinicalTrials.gov
    WAYA-Wilderness OTHER Approved Cancer ClinicalTrials.gov
    Timolol Ophthalmic Solution 0.5 Percent DRUG Phase PHASE2 Open-Angle Glaucoma ClinicalTrials.gov
    Timolol Ophthalmic Suspension 0.5 Percent DRUG Phase PHASE2 Open-Angle Glaucoma ClinicalTrials.gov
    Nebivolol Ophthalmic Suspension 0.5 Percent DRUG Phase PHASE2 Open-Angle Glaucoma ClinicalTrials.gov
    Nebivolol Ophthalmic Suspension 1 Percent DRUG Phase PHASE2 Open-Angle Glaucoma ClinicalTrials.gov
    ketamine DRUG Phase EARLY_PHASE1 Multiple Sclerosis ClinicalTrials.gov
    Hyperbaric Oxygen Therapy DRUG Phase PHASE2 TBI Traumatic Brain Injury ClinicalTrials.gov
    VENDY BEHAVIORAL Phase PHASE4 Harm Reduction ClinicalTrials.gov
    Daraxonrasib (Cohort B1 only) DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    Carboplatin/Cisplatin + Pemetrexed (Cohort B2 Only) DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    cetuximab (Cohort C2 Only) DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    Carboplatin/Cisplatin + Pemetrexed (Dose Expansion Only) DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    Zoldonrasib DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    Elironrasib DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    Daraxonrasib DRUG Phase PHASE1 Advanced Solid Tumors ClinicalTrials.gov
    pemetrexed DRUG Phase PHASE2 Lung Cancer (NSCLC) ClinicalTrials.gov
    carboplatin DRUG Phase PHASE2 Lung Cancer (NSCLC) ClinicalTrials.gov
    FOLFIRI Protocol DRUG Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    Pembrolizumab (KEYTRUDA ®) DRUG Phase PHASE3 Squamous Cell Carcinoma Head and Neck Cancer (HNSCC) ClinicalTrials.gov
    Drug: Ivonescimab Injection DRUG Phase PHASE3 Metastatic Colorectal Cancer (CRC) ClinicalTrials.gov
    FLEXIBLE AND NAVIGATIONAL URETERAL ACCESS SHEATH (FANS) IN FLEXIBLE URETEROSCOPY (FURS) DEVICE Preclinical Urolithiasis ClinicalTrials.gov
    CVAC® SYSTEM DEVICE Preclinical Urolithiasis ClinicalTrials.gov
    Surgical Procedure PROCEDURE Phase PHASE2 Advanced Head and Neck Squamous Cell Carcinoma ClinicalTrials.gov
    Positron Emission Tomography PROCEDURE Phase PHASE2 Advanced Head and Neck Squamous Cell Carcinoma ClinicalTrials.gov
    5-Fluorouracil DRUG Phase PHASE2 Stomach Cancer Stage IV ClinicalTrials.gov
    Docetaxel DRUG Phase PHASE2 TNBC ClinicalTrials.gov
    Questionnaire Administration OTHER Phase PHASE2 Thymus Carcinoma ClinicalTrials.gov
    Magnetic Resonance Imaging PROCEDURE Phase PHASE2 Thymus Carcinoma ClinicalTrials.gov
    Computed Tomography PROCEDURE Phase PHASE2 Thymus Carcinoma ClinicalTrials.gov
    Biospecimen Collection PROCEDURE Phase PHASE2 Thymus Carcinoma ClinicalTrials.gov
    Biopsy Procedure PROCEDURE Phase PHASE2 Thymus Carcinoma ClinicalTrials.gov
    Placebo Injection DRUG Phase PHASE3 Non-Squamous Non-small Cell Lung Cancer ClinicalTrials.gov
    AK112 Injection DRUG Phase PHASE3 Non-Squamous Non-small Cell Lung Cancer ClinicalTrials.gov
    Leucovorin DRUG Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    Capecitabine DRUG Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    Oxaliplatin DRUG Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    AK117 DRUG Phase PHASE2 Metastatic Colorectal Cancer ClinicalTrials.gov
    STrategically Acquired Gradient Echo (STAGE) DEVICE Approved MRI ClinicalTrials.gov
    Ezutromid DRUG Phase PHASE2 Duchenne Muscular Dystrophy ClinicalTrials.gov
    Fidaxomicin DRUG Phase PHASE2 Clostridium Difficile Infection ClinicalTrials.gov
    Ridinilazole DRUG Phase PHASE2 Clostridium Difficile Infection ClinicalTrials.gov
    Vancomycin DRUG Phase PHASE2 Clostridium Difficile Infection ClinicalTrials.gov
    SMT19969 DRUG Phase PHASE2 Clostridium Difficile Infection ClinicalTrials.gov
    SMT C1100 DRUG Phase PHASE1 Duchenne Muscular Dystrophy ClinicalTrials.gov
    Experimental: Adductor Canal perineural local anesthetic infusion DRUG Phase PHASE4 Postoperative Pain Following Knee Arthroplasty ClinicalTrials.gov
    Control: Femoral perineural local anesthetic infusion DRUG Phase PHASE4 Postoperative Pain Following Knee Arthroplasty ClinicalTrials.gov
    perineural ropivacaine PROCEDURE Approved Amputation ClinicalTrials.gov

    💼 Business Developments:

    • Partnership
    • Acquisition
    • Licensing
    • Regulatory Approval
    • Executive Changes: Not available

    Structured Data:

    • Company Name: SUMMIT THERAPEUTICS INC.
    • Ticker Symbol: SMMT

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